Results 101 to 110 of about 5,655,233 (345)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Abundance trend with condensation temperature for stars with different Galactic birth places

, 2016
During the past decade, several studies reported a correlation between chemical abundances of stars and condensation temperature (also known as Tc trend). However, the real astrophysical nature of this correlation is still debated.
Adibekyan, V., Delgado-Mena, E., Faria, J. P., Figueira, P., Hakobyan, A. A., Harutyunyan, G., Hernandez, J. I. Gonzalez, Israelian, G., Minchev, I., Santos, N. C., Sousa, S. G., Suarez-Andres, L.   +11 more
core   +1 more source

Using Bi-Temporal Lidar to Evaluate Canopy Structure and Ecotone Influence on Landsat Vegetation Index Trends Within a Boreal Wetland Complex

Applied Sciences
Wetland ecosystems are sensitive to climate variation, yet tracking vegetation type and structure changes through time remains a challenge. This study examines how Landsat-derived vegetation indices (NDVI and EVI) correspond with lidar-derived canopy ...
Farnoosh Aslami, Chris Hopkinson, Laura Chasmer, Craig Mahoney, Daniel L. Peters   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Trending Videos: Measurement and Analysis

CoRR, 2014
Unlike popular videos, which would have already achieved high viewership numbers by the time they are declared popular, YouTube trending videos represent content that targets viewers attention over a relatively short time, and has the potential of becoming popular.
Iman Barjasteh, Ying Liu 0017, Hayder Radha   +2 more
openaire   +2 more sources

An Investigation of the Changes in the Iran Precipitation Extreme Indices in Two Normal Climate Periods, 1981-2010 and 2020-1991 [PDF]

Nīvār
Precipitation fluctuation is a critical factor in understanding climate, as it has far-reaching impacts on the environment, economy, and society. Excessive or insufficient precipitation can result in severe floods and droughts, causing significant ...
Zohreh Javanshiri, Ebrahim Asadi Oskouei, Fatemeh Abbasi   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Polluting emissions and GDP : decoupling evidence from brazilian states [PDF]

, 2019
We provide a comprehensive analysis of the relationship between greenhouse gas (GHG) emissions and GDP in Brazil using both aggregate and state-level data.
Jalles, João Tovar
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source