Results 161 to 170 of about 30,405,915 (378)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals

Frontiers in Public Health
ObjectiveExploring the Incidence, Epidemic Trends, and Spatial Distribution Characteristics of Sporadic Hepatitis E in Hainan Province from 2013 to 2022 through four major tertiary hospitals in the Province.MethodsWe collected data on confirmed cases of ...
Zhi Yun, Panpan Li, Jinzhong Wang, Feng Lin, Wenting Li, Minhua Weng, Yanru Zhang, Huazhi Wu, Hui Li, Xiaofang Cai, Xiaobo Li, Xianxian Fu, Tao Wu, Tao Wu, Yi Gao   +14 more
doaj   +1 more source

Trend Analysis

, 1996
This chapter addresses the problem of reliability growth analysis; it shows how reliability trend analyses can help the project manager control the progress of the development activities and appreciate the efficiency of the test programs. Reliability trend changes occur for various reasons. They may be desirable and expected (such as reliability growth
Kanoun, Karama, Laprie, Jean-Claude
openaire   +1 more source

Explaining trends and patterns in attitudes towards wife-beating among women in Nigeria: analysis of 2003, 2008, and 2013 Demographic and Health Survey data [PDF]

, 2016
Kolawole Azeez Oyediran
openalex   +1 more source

Trends and cycles in regional economic growth : how spatial differences formed the Swedish growth experience 1860-2009. [PDF]

Using a novel dataset on regional GDP per worker 1860-2009, this paper analyzes communalities in regional long-term growth trajectories for 24 Swedish provinces.
Andersson, Fredrik NG, Enflo, Kerstin, Henning, Martin   +2 more
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Trend Analysis of MODIS Land Surface Temperature and Land Cover in Central Italy

Land
Land Surface Temperature (LST) is an important climate factor for understanding the relationship between the land surface and atmosphere. Furthermore, LST is linked to soil moisture and evapotranspiration, which can potentially alter the severity and ...
Ebrahim Ghaderpour, Paolo Mazzanti, Francesca Bozzano, Gabriele Scarascia Mugnozza   +3 more
doaj   +1 more source

Current Status of and Global Trends in Platelet Transfusion Refractoriness From 2004 to 2021: A Bibliometric Analysis

, 2022
Ying Liu, Yufan Zhang, Dawei Chen, Yongshui Fu   +3 more
openalex   +1 more source

Support for resistance: technical analysis and intraday exchange rates [PDF]

“Support” and “resistance” levels—points at which an exchange rate trend may be interrupted and reversed—are widely used for short-term exchange rate forecasting.
Carol Osler
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source