Results 171 to 180 of about 30,405,915 (378)

Global Research Trends in Pediatric Trauma From 1968 to 2021: A Bibliometric Analysis

open access: gold, 2021
Tauseef Ahmad   +10 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Statistical analysis of stratospheric temperature and ozone profile data for trends and model comparison [PDF]

open access: yes
Work performed during the project period July 1, 1990 to June 30, 1992 on the statistical analysis of stratospheric temperature data, rawinsonde temperature data, and ozone profile data for the detection of trends is described.
Tiao, G. C.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Trend analysis in two standard growth models [PDF]

open access: yes
This paper analyzes the trend processes characterized by two standard growth models using simple econometrics. The first model is the basic neoclassical growth model that postulates a deterministic trend for output.
Restrepo Ochoa, Sergio I.   +1 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

1990—2021年中国青少年和青年人群脑出血发病趋势及年龄-时期-队列模型分析(The Incidence Trend and Age-Period-Cohort Model Analysis of Intracerebral Hemorrhage in Adolescents and Young Adults in China from 1990 to 2021)

open access: yesZhongguo cuzhong zazhi
目的 探究1990—2021年中国青少年和青年人群脑出血的发病趋势及其受年龄、时期和队列因素影响的效应,旨在为防控策略的制定提供科学依据。 方法 本研究基于2021年的全球疾病负担(global burden of disease,GBD)数据库,根据世界卫生组织和中国国家统计局的相关标准,纳入1990—2021年中国15~39岁青少年和青年人群,分析其脑出血发病情况,运用Joinpoint软件评估标化发病率趋势并计算年度变化百分比和平均年度变化百分比(average annual ...
丁月明1,张冰莹2,孙琳琳2,吕思谕3,金海2,郝广志2 (DING Yueming1, ZHANG Bingying2, SUN Linlin2, LYU Siyu3, JIN Hai2, HAO Guangzhi2 )
doaj   +1 more source

Source of Output dynamics in USA vs. Great Britain: supply, demand or nominal shocks [PDF]

open access: yes
The purpose of the present paper is to extend Clarida and Gali (1994) from structural specification to common trend specification and to study the relative importance of nominal, supply and demand shocks in relative output dynamics.
Rzigui, Lotfi
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Spatio-temporal variations of vegetation cover and its influencing factors in highland lake basin

open access: yesFrontiers in Environmental Science
Exploring dynamic vegetation changes and identifying the factors driving these changes are important for evaluating global ecosystem processes. Based on the pixel binary model, coefficient of variation, Theil-Sen median trend analysis, geographic ...
Zhoujiang Liu   +3 more
doaj   +1 more source

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