Results 211 to 220 of about 195,282 (301)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Clinical epidemiology, microbiology, and care of war-related wounds in Ukraine. [PDF]

J Trauma Acute Care Surg
Trent SA, Beaty L, Peers J, Simon S, Scovorodniev A, Kireeva I, Fishchuk R, Carlson NE, Ginde AA, Bills CB, Denver, Colorado.   +11 more
europepmc   +1 more source

Disrupting the Child Welfare Participation Paradigm: A Contextual, Relational, Embedded and Pragmatic Approach

Child &Family Social Work, EarlyView.
ABSTRACT Child and parent participation is fundamental to effective child welfare practice. Legislative imperatives assert the right to participate, but in a child welfare context, participation is complex and risks becoming rhetorical. This paper, based on a conceptual synthesis built from second person action research and a narrative review, explores
Jeri L. Damman, Teresa Bertotti, Diletta Mauri, Gillian Ruch, Karen Winter   +4 more
wiley   +1 more source

Interactive Groupwise Comparison for Reinforcement Learning from Human Feedback

Computer Graphics Forum, EarlyView.
The standard RLHF uses pairwise comparisons and therefore requires a large number of comparisons leading to a high workload. The comparison pairs are suggested by the system and cannot be chosen by the user. Our RLHF approach provides more agency to the user and demands less work: we leverage the user's visual abilities to effectively explore the ...
Jan Kompatscher, Danqing Shi, Giovanna Varni, Tino Weinkauf, Antti Oulasvirta   +4 more
wiley   +1 more source

Multiomic Landscape of Gastrointestinal Stromal Tumors in a Real-World Patient Cohort of 1,427 Cases. [PDF]

Clin Cancer Res
Serrano C, Elliott A, Gómez-Peregrina D, Evans MG, George S, von Mehren M, Maki RG, Boikos SA, Charlson JA, Dhir A, Florou V, Mahadevan D, Oberley MJ, Sledge GW, Tinoco G, Riedel RF, Trent JC.   +16 more
europepmc   +1 more source

Oxygen uptake of rainbow trout during acute warming: effects of oxygen supersaturation and aerobic exercise. [PDF]

J Exp Biol
Bellinger IG, Reid HB, Raby GD.
europepmc   +1 more source