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Molecular Subtyping of Treponema pallidum Subspecies pallidum
Sexually Transmitted Diseases, 1998Epidemiologic studies on syphilis have been hampered by the fact that strains of Treponema pallidum subspecies pallidum (T. pallidum), the causative agent of this disease, cannot be differentiated by either protein-based or deoxyribonucleic acid-based methods. Syphilis is endemic in many developing countries and is common in some industrialized nations.
A, Pillay +6 more
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Azithromycin resistance in Treponema pallidum
Current Opinion in Infectious Diseases, 2008Although the recommended treatment for syphilis is penicillin, azithromycin has been used as an alternative. We discuss azithromycin-related treatment failures and resistance in Treponema pallidum, and propose ways to meet the resulting clinical and public health challenges.Azithromycin treatment failures in syphilis were first noted in San Francisco ...
Kenneth A, Katz, Jeffrey D, Klausner
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1994
Publisher Summary This chapter discusses the culture of Treponerna pallidum ( T. pallidum ). T. pallidum can be cultivated in a variety of tissue culture vessels; 24-, 12-, and 6-well culture plates, and 25-, 75-, and 150-cm 2 tissue culture flasks, have been used successfully to cultivate T. pallidum .
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Publisher Summary This chapter discusses the culture of Treponerna pallidum ( T. pallidum ). T. pallidum can be cultivated in a variety of tissue culture vessels; 24-, 12-, and 6-well culture plates, and 25-, 75-, and 150-cm 2 tissue culture flasks, have been used successfully to cultivate T. pallidum .
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Molecular biology of Treponema pallidum
1992The spirochaete Treponema pallidum subsp. pallidum, the causative agent of the venereal disease syphilis, has been the subject of extensive studies ever since its discovery over eighty years ago. The study of this pathogen has been hampered by inability to cultivate the pathogenic treponemes in vitro. The last decade a number of investigators have used
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Bottleneck and spread of Treponema pallidum
Nature Reviews Microbiology, 2021openaire +2 more sources