Results 91 to 100 of about 254 (146)

TREX Targeting REal Accuracy at eXascale

, 2021
In order to compete in the demanding rush in high-precision quantum chemical simulation methods, the TREX Center of Excellence (CoE) federates European scientists, High Performance Computing (HPC) stakeholders, and SMEs to develop and apply high-performance software solutions for quantum mechanical simulations at the exascale.
openaire   +2 more sources

D7.1 – TREX Branding and communication kit

, 2020
This document is therefore intended to report about the TREX Branding and Communication Kit, one of the first online tools developed to pursue an optimal development of the TREX brand and visual identity and to start spreading project recognition among relevant stakeholder groups while unifying the style of the communication revolving around the ...
openaire   +1 more source

Early and Sustained Comprehensive Symptom Control, Including Bowel Urgency and Fatigue, With Mirikizumab in Crohn's Disease: An Exploratory Post Hoc Analysis of the Phase 3 VIVID‐1 Study

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background and Aims In this exploratory post hoc analysis of the phase 3 VIVID‐1 (NCT03926130) study, we evaluate early and sustained treatment effects of mirikizumab on individual disruptive CD symptoms—stool frequency (SF), abdominal pain (AP), bowel urgency (BU) and fatigue—in non‐biologic‐failed (NBF) and biologic‐failed (BF) patients and ...
Axel Dignass, Silvio Danese, Jessica R. Allegretti, Sami Hoque, Minhu Chen, Katsuyoshi Matsuoka, Iago Rodríguez‐Lago, Sebastian Maier, Emily Hon, Chunyuan Liu, Guanglei Yu, Isabel Redondo, Bruce E. Sands   +12 more
wiley   +1 more source

Unraveling gene expression: a beginner’s guide from chromatin modifications to mRNA export in Saccharomyces cerevisiae

Nucleus
Understanding gene expression requires grasping its multi-step processes, from chromatin remodeling to mRNA export. This manuscript provides an accessible entry point for PhD students and junior postdocs beginning research in this area, using yeast as a ...
Joan Serrano-Quílez, Susana Rodriguez-Navarro   +1 more
doaj   +1 more source

Bimekizumab 2‐year efficacy by hidradenitis suppurativa duration: BE HEARD EXT results

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Raj Chovatiya, Afsaneh Alavi, Takuya Miyagawa, Irina Turchin, Thrasyvoulos Tzellos, Hessel H. van der Zee, Christina Crater, Bartosz Lukowski, Nicola Tilt, Christos C. Zouboulis   +9 more
wiley   +1 more source

Hardware‐Efficient Hamiltonian Simulation via Trotter‐Initialized Variational Optimization With Native Placement

Advanced Quantum Technologies, Volume 9, Issue 9, September 2026.
A new physics‐informed compilation framework bridges the gap between theoretical quantum simulations and noisy NISQ hardware. By combining native qubit placement with adaptive, variational circuit synthesis, this approach drastically reduces circuit depth and circumvents device noise, unlocking high‐fidelity quantum simulations on current processors ...
F. S. Luiz, P. N. Ferreira, M. C. de Oliveira   +2 more
wiley   +1 more source

Conceptualizing moral migration: how disillusionment and the transnational right motivate migration to Russia Conceptualiser la migration morale : comment les désillusions et la droite transnationale motivent l’émigration vers la Russie

Journal of the Royal Anthropological Institute, Volume 32, Issue 3, Page 888-906, September 2026.
Russia is consistently a top migration destination. While most migrate to Russia from other post‐Soviet countries, a small but highly visible group of the Russian‐speaking diaspora has returned from Europe and North America. Lauded in Russian media as ‘ideological migrants’, their narratives at first glance echo those of the state as they claim to flee
Lauren Woodard
wiley   +1 more source

The Questioning of Special Items During Conference Calls: High Quality or Highly Questionable? Réexaminer des éléments exceptionnels lors des conférences téléphoniques : une pratique d'excellence ou très contestable?

Contemporary Accounting Research, Volume 43, Issue 3, Page 1651-1681, Fall 2026.
ABSTRACT Accounting standards require firms to distinguish recurring revenues and expenses from nonrecurring gains and losses, which are often referred to as special items. However, not all special items are genuinely nonrecurring. Exploiting the setting of earnings conference calls, we explore whether analysts can identify opportunistic special items,
Jiajia Fu, Yuan Ji, James Potepa
wiley   +1 more source

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

Nature Communications
We implicated the X-chromosome THOC2 gene, which encodes the largest subunit of the highly-conserved TREX (Transcription-Export) complex, in a clinically complex neurodevelopmental disorder with intellectual disability as the core phenotype. To study the
Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz   +23 more
doaj   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter, Ian M. Adcock, Cristina Benito‐Villalvilla, Rodolfo Bianchini, Leif Bjermer, Gaetano Caramori, Luigi Cari, Kian Fan Chung, Zuzana Diamant, Ibon Eguiluz‐Gracia, Edward F. Knol, Milos Jesenak, Francesca Levi‐Schaffer, Giuseppe Nocentini, Liam O'Mahony, Oscar Palomares, Frank Redegeld, Milena Sokolowska, Betty Van Esch, Marco Zurlo, Cristiana Stellato   +20 more
wiley   +1 more source