Results 91 to 100 of about 278,419 (266)

Digital Entrepreneurship: The Role of Digital Marketing, Human Capital and Entrepreneurship Orientation On The Success of Small and Medium Culinary Business

open access: yesIndonesian Journal of Business and Entrepreneurship
Background: In the digital transformation era, digital technology is one of the main strategies for business actors to succeed, especially in facing increasingly tight competition. By utilizing digital technology, entrepreneurs can reach a broader market,
Asmawiyah Asmawiyah   +2 more
doaj   +1 more source

Tri kuće, tri izvora

open access: yesPlaymath, 2006
U članku se promatra sljedeći problem. Nacrtane su tri kuće i tri bunara. Spojite svaku od kuća sa svim trima bunarima tako da se linije ne sijeku.
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio combination for acute coronary syndrome risk stratification: A retrospective observational study from a Metropolitan Medical Center in Taiwan

open access: yesScience Progress
Objective To evaluate the prognostic value of the combined neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) for adverse outcomes in Taiwanese patients with acute coronary syndrome (ACS).
Yu-Cheng Chen   +22 more
doaj   +1 more source

Stability of Tri-Homomorphisms, Tri-Derivations, and Tri-Isomorphisms in C*-Ternary Algebras

open access: yesMathematics
This work demonstrates the generalized Hyers–Ulam stability of tri-homomorphisms within C∗-ternary algebras. We investigate the stability of a tri-additive functional equation and apply these results to study tri-derivations and tri-isomorphisms between C∗-ternary algebras.
Jae-Hyeong Bae, Won-Gil Park
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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