Results 171 to 180 of about 137,161 (312)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

open access: yesInterdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang   +7 more
wiley   +1 more source

Integrating Prostate‐Specific Antigen Density and Prostate Imaging Reporting and Data System Scores to Optimize Detection of Clinically Significant Prostate Cancer: A Multivariable Risk Model Approach

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
For the detection of clinically significant prostate cancer, incorporating PSA density into PI‐RADS‐based assessment improved clinical net benefit compared with PI‐RADS alone. The addition of DRE and age to this combined model produced only marginal further gain, indicating that most of the incremental clinical value was derived from PSA density rather
Yunus Kayali
wiley   +1 more source

Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In nonspecialist departments, most anti‐HCV–positive individuals do not proceed to RNA testing. The Elecsys HCV Duo assay simultaneously detects anti‐HCV antibodies and core antigen from a single blood draw and preferentially identifies patients with clinically meaningful viral loads.
Hiroko Setoyama   +23 more
wiley   +1 more source

Generative Artificial Intelligence–Driven Clinical Case Simulation in Temporomandibular Disorder Education: ChatGPT Versus Real Patients

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Background Temporomandibular disorders (TMDs) and orofacial pain (OFP) demand advanced diagnostic and clinical reasoning skills in dental education. Traditional simulations with real patients face limitations in availability and standardization.
Paula Rodrigues‐Pereira   +7 more
wiley   +1 more source

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