Results 41 to 50 of about 188,631 (352)

Putting ICU triage guidelines into practice: A simulation study using observations and interviews

PLoS ONE, 2023
Background The COVID-19 pandemic has prompted many countries to formulate guidelines on how to deal with a worst-case scenario in which the number of patients needing intensive care unit (ICU) care exceeds the number of available beds. This study aims to
Inger L. Abma, Gert J. Olthuis, Irma T. H. M. Maassen, Marjan L. Knippenberg, Miriam Moviat, Annie J. Hasker, A. G. Buenen, Bernard G. Fikkers, Anke J. M. Oerlemans   +8 more
doaj   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Improving triage performance in emergency departments using machine learning and natural language processing: a systematic review

BMC Emergency Medicine
In Emergency Departments (EDs), triage is crucial for determining patient severity and prioritizing care, typically using the Manchester Triage Scale (MTS). Traditional triage systems, reliant on human judgment, are prone to under-triage and over-triage,
Bruno Matos Porto
semanticscholar   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Exploring Diagnostic Precision and Triage Proficiency: A Comparative Study of GPT-4 and Bard in Addressing Common Ophthalmic Complaints

Bioengineering
In the modern era, patients often resort to the internet for answers to their health-related concerns, and clinics face challenges to providing timely response to patient concerns. This has led to a need to investigate the capabilities of AI chatbots for
Roya Zandi, Joseph D Fahey, Michael Drakopoulos, John M. Bryan, Siyuan Dong, Paul J. Bryar, Ann E. Bidwell, R. Bowen, Jeremy A. Lavine, R. Mirza   +9 more
semanticscholar   +1 more source

Triage Accuracy of Symptom Checker Apps: 5-Year Follow-up Evaluation

Journal of Medical Internet Research, 2021
Background Symptom checkers are digital tools assisting laypersons in self-assessing the urgency and potential causes of their medical complaints.
Malte L Schmieding, Marvin Kopka, K. Schmidt, Sven Schulz-Niethammer, F. Balzer, M. Feufel   +5 more
semanticscholar   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

NoDoze: Combatting Threat Alert Fatigue with Automated Provenance Triage

Network and Distributed System Security Symposium, 2019
—Large enterprises are increasingly relying on threat detection softwares (e.g., Intrusion Detection Systems) to allow them to spot suspicious activities.
Wajih Ul Hassan, Shengjian Guo, Ding Li, Zhengzhang Chen, Kangkook Jee, Zhichun Li, Adam Bates   +6 more
semanticscholar   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Evaluation of a Conference on Cancer-Related Financial and Legal Issues: A Potential Resource to Counter Financial Toxicity

Current Oncology
This study describes the conception, development, and growth of the Triage Cancer Conference hosted by Triage Cancer, a national nonprofit organization providing free legal and financial education to the cancer community.
Lauren V. Ghazal, Joanna Doran, Monica Bryant, Brad Zebrack, Margaret I. Liang   +4 more
doaj   +1 more source