Results 151 to 160 of about 7,719,266 (361)

Organic Winter Wheat Variety Trial Report [PDF]

open access: yes, 2014
In 2014, the University of Vermont Extension conducted an extensive organic variety trial to evaluate hard red winter wheat in order to determine which varieties thrive in the Northeast.
Cummings, Erica   +4 more
core   +1 more source

Efficacy and Safety of an Inactivated Whole-Virion Vaccine Against COVID-19, QazCovid-in®, In Healthy Adults: A Multicentre, Randomised, Single-Blind, Placebo-Controlled Phase 3 Clinical Trial With a 6-Month Follow-Up

open access: green, 2022
Berik Khairullin   +22 more
openalex   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Flax Weed Control Trial [PDF]

open access: yes, 2016
Flax (Linum usitatissimum L.) is a multi-purpose crop grown for its fiber, oil (linseed oil), and meal. The majority of production occurs in the Dakotas, Minnesota, and Montana.
Brigham, Nate   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Three approaches to determining clinically meaningful benefit on the Cohen‐Mansfield Agitation Inventory in dementia clinical trials for agitation

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION There is a need to understand the clinical meaningfulness of symptom score changes in treatment trials of dementia‐related agitation. We estimated minimal clinically important differences (MCIDs) for commonly employed agitation scales and ...
Kathy Y. Liu   +9 more
doaj   +1 more source

Winter Barley Variety Trial [PDF]

open access: yes, 2012
With the revival of the small grains industry in the Northeast and the strength of the localvore movement, craft breweries and distilleries have expressed an interest in local barley for malting.
Darby, Heather
core   +1 more source

Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy [PDF]

open access: bronze, 2018
Kassandra L. Munger   +53 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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