Results 181 to 190 of about 2,302,312 (219)

"Within-Trial" Prognostic Score Adjustment Is Targeted Maximum Likelihood Estimation. [PDF]

Pharm Stat
Højbjerre-Frandsen E, Schuler A.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Initial low and moderate dose of hydroxyurea has a durable impact on primary stroke prevention in low-income settings. [PDF]

Blood Adv
Abdullahi SU, Galadanci NA, Bello-Manga H, Ibrahim UA, Jibir BW, Yusuf AH, Galadanci JA, Rodeghier M, DeBaun MR.   +8 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Guide on Selection of Optimal Motivational Themes for Use in a Clinical Trial Recruiting Black US Adults: Survey Study.

J Med Internet Res
Harry T, Cao J, Hussain Z, Turkson-Ocran RN, Juraschek SP, Lahey TP, Plante TB, Feng Y.   +7 more
europepmc   +1 more source

Petit volunteer protocol for loneliness alleviation in community-dwelling older adults in Japan: a randomised controlled trial. [PDF]

BMJ Open
Tomida K, Shimoda T, Nakajima C, Kawakami A, Shimada H.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Revisiting the Immune Frontier in Soft Tissue Sarcomas. [PDF]

Curr Oncol Rep
Bilani N, Al Akoum N, Al-Marayaty R, Orlando S, Alexiev B, de Viveiros PH, Pollack SM.   +6 more
europepmc   +1 more source

Comment on: Efficacy of intracameral moxifloxacin in prevention of postcataract surgery endophthalmitis: randomized control trial. [PDF]

J Cataract Refract Surg
Tello A, Galvis V.
europepmc   +1 more source