Results 121 to 130 of about 397,654 (324)
Zygon, 1982 This essay examines current decision‐making procedures in politics, especially those employed in parliamentary procedure, with a view to determining the extent to which they contribute to the making of rational political decisions.
doaj +2 more sources
Complex Scientific Testimony: Can Educational Psychology Turn Jurors Into Students and Lawyers Into Teachers? [PDF]
, 1998 Jury trials are an integral part of the United States system of justice. However, as of late, the institution of the jury has been attacked on the front that much of the testimony presented to jurors is too complex for them to comprehend.
Krebs \u2798, Jason A.
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Post-trial obligations - DOI: 10.3395/reciis.v2.Sup1.210en
RECIIS, 2008 In its essence, post-trial obligations describe a duty by research sponsors to provide a successfully tested drug to research participants who took part in the relevant clinical trials after the trial has been concluded.
Doris Schroeder
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RevSALUSThe decision of the jury in criminal trials is widely regarded as a cornerstone of democratic judicial systems, based on the premise that impartial individuals can objectively judge a case. However, a growing body of research suggests that psychological
João Miguel Alves Ferreira +1 more
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Terrorism and Trial by Jury: The Vices and Virtues of British and American Criminal Law [PDF]
, 2007 British tradition and the American Constitution guarantee trial by jury for serious crime. But terrorism is not ordinary crime, and the presence of jurors may skew the manner in which terrorist trials unfold in at least three significant ways.
Donohue, Laura K.
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
06-12-1986 Justice Powell, Per Curiam [PDF]
, 1986 In 1978, petitioner Earl Allen, a black man, was indicted for murdering his girlfriend and her brother. During selection of the petit jurors at petitioner\u27s trial, the prosecutor exercised 9 of the State\u27s 17 peremptory challenges to strike 7 black
Powell, Lewis F
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source