Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Trial of labor following cesarean among patients with oligohydramnios at term: A multicenter retrospective study. [PDF]
Weiss A +5 more
europepmc +1 more source
Changes in lower uterine segment thickness during different gestational weeks in pregnant women qualified for trial of labor after cesarean section. [PDF]
Rao J +9 more
europepmc +1 more source
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Maternal morbidity following a trial of labor after cesarean birth: A scoping review of operative vaginal birth compared with cesarean birth in the second stage of labor. [PDF]
Oltean II, Hébert V, Muraca GM.
europepmc +1 more source
Obstetricians' perspectives on trial of labor after cesarean (TOLAC) under the two-child policy in China: a cross-sectional study. [PDF]
Luo ZC +8 more
europepmc +1 more source
A Supramolecular Reversible and Anisotropic Conductive Adhesive for Flexible Electronics
Supramolecular network‐based nanocomposites are developed as a stretchable conductive adhesive for flexible electronics. It's as convenient as traditional solders and constructs anisotropic conductive and robust stretchable connections among diverse soft/rigid materials.
Tongtong Li +8 more
wiley +1 more source
Trial of labor when twin B is slightly larger than twin A: A Danish prospective cohort study. [PDF]
Khalil MR +5 more
europepmc +1 more source
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Impact of health literacy and primary language on the decision to pursue trial of labor after prior cesarean delivery. [PDF]
Leon-Martinez D +6 more
europepmc +1 more source

