Results 51 to 60 of about 696,938 (351)

Process evaluation for complex interventions in primary care: understanding trials using the normalization process model [PDF]

, 2007
Background: the Normalization Process Model is a conceptual tool intended to assist in understanding the factors that affect implementation processes in clinical trials and other evaluations of complex interventions.
A Nezu, A Oakley, A Strauss, B Blackwood, B Flyvbjerg, B Starfield, C Dowrick, C Dowrick, C Dowrick, C May, C May, C May, Carl R May, CB Stetler, Christopher F Dowrick, D Silverman, DA Richards, EM Rogers, F Badger, F Lloyd-Williams, F Lloyd-Williams, F Mair, FM Task, Frances S Mair, FS Mair, H Charles-Jones, I Ajzen, J Grimshaw, J Ogden, J Sturt, JE Barret, JGF Cleland, JK Ghali, JS Coleman, JS Hacker, K Gravel, K Hawton, L Mynors-Wallis, L Mynors-Wallis, L Robinson, LA Suchman, LH Harpole, M Eccles, M Lainscak, M Laurant, Medical Research Council, MK Davies, P Berger, P Lehoux, P Lehoux, RE Glasgow, S Cocksedge, S Flottorp, S Levine, S Stewart, S Stewart, SA Hunt, SG Riedel-Heller, SJ Tanenbaum, SM Campbell, SM Campbell, T Kendrick, T Morris, TJ Fararo, Tracy L Finch, WJ Katon   +65 more
core   +6 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Repeat cesarean section in subsequent gestation of women from a birth cohort in Brazil

Reproductive Health, 2017
Background The current literature indicates increasing concern regarding the number of safe cesarean sections which a woman can undergo, mainly in face of the high cesarean section rates, which are growing in Brazil and worldwide.
Keila Cristina Mascarello, Alicia Matijasevich, Aluísio J D Barros, Iná S Santos, Eliana Zandonade, Mariângela Freitas Silveira   +5 more
doaj   +1 more source

Outcome of subsequent pregnancies in women with complete uterine rupture: A population‐based case–control study

Acta Obstetricia et Gynecologica Scandinavica, 2022
Introduction In the attempt of a trial of labor after a cesarean section approximately one in 200 women experience a complete uterine rupture. As a complete uterine rupture is associated with an adverse perinatal outcome, data regarding subsequent ...
Dorthe Louise Ahrenkiel Thisted, Steen Christian Rasmussen, Lone Krebs   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Labor patterns in Chinese women in Fuzhou attempting vaginal birth after previous cesarean delivery: a retrospective cohort study

Journal of International Medical Research, 2019
Objective To investigate the characteristics of labor in Chinese women who successfully have vaginal birth after cesarean section (VBAC). Methods A retrospective cohort study was conducted in a hospital with 1000 beds between January 1 2015 and December ...
Lianghui Zheng, Qinjian Zhang, Qiuping Liao, Rongxin Chen, Rongli Xu, Qing Han, Jianying Yan   +6 more
doaj   +1 more source

Indirect effects of an aid program: how do liquidity injections affect non-eligibles' consumption? [PDF]

, 2006
Aid programs in developing countries are likely to affect both the treated and the non-treated households living in the targeted areas. Studies that focus on the treatment effecton the treated may fail to capture important spillover effects.
Angelucci, M, De Giorgi, G
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source