Results 11 to 20 of about 926,305 (280)

Change over Five Years in Important Measures of Methodological Quality and Reporting in Randomized Cardiovascular Clinical Trials

Journal of Cardiovascular Development and Disease, 2023
Objectives: The aim of our current study was to analyze whether the use of important measures of methodological quality and reporting of randomized clinical trials published in the field of cardiovascular disease research haschanged over time.
Odgerel Baasan, Omar Freihat, Dávid U. Nagy, Szimonetta Lohner   +3 more
doaj   +1 more source

Methodological Quality and Risk of Bias Assessment of Cardiovascular Disease Research: Analysis of Randomized Controlled Trials Published in 2017

Frontiers in Cardiovascular Medicine, 2022
BackgroundAll randomized-controlled trials (RCTs) are required to follow high methodological standards. In this study, we aimed to assess the methodological quality of published cardiovascular clinical research trials in a representative sample of RCTs ...
Odgerel Baasan, Odgerel Baasan, Omar Freihat, David U. Nagy, David U. Nagy, Szimonetta Lohner, Szimonetta Lohner   +6 more
doaj   +1 more source

Evaluating prospective study registration and result reporting of trials conducted in Canada from 2009 to 2019

FACETS, 2023
Adherence to study registration and reporting best practices is vital to fostering evidence-based medicine. All registered clinical trials on ClinicalTrials.gov conducted in Canada as of 2009 and completed by 2019 were identified.
Mohsen Alayche, Kelly D. Cobey, Jeremy Y. Ng, Clare L. Ardern, Karim M. Khan, An-Wen Chan, Ryan Chow, Mouayad Masalkhi, Ana Patricia Ayala, Sanam Ebrahimzadeh, Jason Ghossein, Ibrahim Alayche, Jessie V. Willis, David Moher   +13 more
doaj   +1 more source

DATA SHARING: A NEW EDITORIAL INITIATIVE OF THE INTERNATIONAL COMMITTEE OF MEDICAL JOURNAL EDITORS. IMPLICATIONS FOR THE EDITORS´ NETWORK

Российский кардиологический журнал, 2017
The International Committee of Medical Journal Editors (ICMJE) provides recommendations to improve the editorial standards and scientific quality of biomedical journals.
Network Editors’
doaj   +3 more sources

Pilot Test of Dosage Effects in HEXORR II for Robotic Hand Movement Therapy in Individuals With Chronic Stroke

Frontiers in Rehabilitation Sciences, 2021
Impaired use of the hand in functional tasks remains difficult to overcome in many individuals after a stroke. This often leads to compensation strategies using the less-affected limb, which allows for independence in some aspects of daily activities ...
Ji Chen, Ji Chen, Iian Black, Iian Black, Diane Nichols, Tianyao Chen, Melissa Sandison, Melissa Sandison, Rafael Casas, Rafael Casas, Peter S. Lum, Peter S. Lum   +11 more
doaj   +1 more source

Comprehensive Survey of Clinical Trials Registration for Melanoma Immunotherapy in the ClinicalTrials.gov

Frontiers in Pharmacology, 2020
Objective: Comprehensively evaluate the immunotherapeutic clinical trials and provide reference for melanoma treatment and research.Methods: The website of ClinicalTrials.gov was searched to retrieve and download all registered clinical trials for ...
Yan-Bo Wang, Gang Lv, Feng-Hua Xu, Lin-Lu Ma, Yong-Ming Yao   +4 more
doaj   +1 more source

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.), Brosens, Jan J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Fishwick, Katherine, Fujihara, Risa, Kimani, Peter K., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Polanco, Angela, Quenby, Siobhan, Takeda, Satoru, Tewary, Shreeya   +13 more
core   +1 more source

Monoclonal antibodies: new chance in the management of B-cell acute lymphoblastic leukemia

Hematology, 2022
Objectives This review aims to see the progress of several clinically-used monoclonal antibodies in treating ALL patients and how they improved patients' outcomes.Methods We searched Web of Science, Elsevier and PubMed for relevant published studies, and
Zheng Shi, Yiqian Zhu, Jing Zhang, Baoan Chen   +3 more
doaj   +1 more source

The GoodNight study—online CBT for insomnia for the indicated prevention of depression: study protocol for a randomised controlled trial [PDF]

, 2016
BACKGROUND Cognitive Behaviour Therapy for Insomnia (CBT-I) delivered through the Internet is effective as a treatment in reducing insomnia in individuals seeking help for insomnia. CBT-I also lowers levels of depression in this group. However, it is not
Bennett, Anthony, Bennett, Kylie, Christensen, Helen, Glozier, Nick, Gosling, John A., Griffiths, Kathleen, Hehir, Kanupriya Kalia, Mackinnon, Andrew, Ritterband, Lee, Thorndike, Frances   +9 more
core   +1 more source

Trends in global clinical trial registration: an analysis of numbers of registered clinical trials in different parts of the world from 2004 to 2013. [PDF]

, 2015
OBJECTIVES: To analyse developments (and their causes) in the number and proportion of clinical trials that were registered in different parts of the world after the International Committee of Medical Journal Editors (ICMJE) announced in 2004 that it ...
Li, Keyang, Viergever, Roderik F
core   +1 more source