Results 31 to 40 of about 926,305 (280)

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]

, 2012
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H., Cooke, Matthew, Hawkey, P. M., Hong, Tan, Jones, Alan, Linhartova, Lucie, Melody, Teresa, Patel, Jaimin M., Perkins, Gavin D., Smith, F. Gao, Snaith, Catherine, Thickett, David R.   +11 more
core   +3 more sources

Effectiveness of guided self-help in decreasing expressed emotion in family caregivers of people diagnosed with depression in Thailand: a randomised controlled trial [PDF]

, 2015
Background: High expressed emotion (EE) can extend the duration of illness and precipitate relapse; however, little evidence-based information is available to assist family caregivers of individuals with depression.
A Cechnicki, A Heru, A Vikas, AB Phipps, AF Jorm, AG Weisman, AM Heru, C Vaughn, CE Vaughn, D Bhugra, D Eckshtain, D Eckshtain, E Kuipers, E McCauley, G Wiedemann, H Sethabouppha, J Gellatly, JM Hooley, JM Hooley, John Stephenson, JP Leff, K Kumar, LF Campbell, LL Bilich, MY Chiu, N Berglund, P Cuijpers, PL Watkins, RJ Gregory, RL Butzlaff, Terence V. McCann, TV McCann, TV McCann, TV McCann, W Songprakun, W Songprakun, W Songprakun, Wallapa Songprakun, World Health Organisation and Ministry of Public Health, World Health Organization   +39 more
core   +2 more sources

An audit of studies registered retrospectively with the Clinical Trials Registry of India: A one year analysis

Perspectives in Clinical Research, 2019
Background: The Clinical Trials Registry of India (CTRI) was launched in July 2007 and will enter its tenth year in 2017. While its mission is to encourage prospective trial registration, CTRI does permit retrospective trial registration.
Amit R Birajdar, Debdipta Bose, Tushar B Nishandar, Anagha A Shende, Urmila M Thatte, Nithya J Gogtay   +5 more
doaj   +1 more source

A new parenting-based group intervention for young anxious children: results of a randomized controlled trial [PDF]

, 2011
Objective Despite recent advances, there are still no interventions that have been developed for the specific treatment of young children who have anxiety disorders.
Cartwright-Hatton, Sam, Dixon, Clare, Field, Andy P, Gallagher, Bridie, Harrington, Richard, Laskey, Ben, McNally, Deb, Miller, Chloe, Pemberton, Kathryn, Rust, Stewart, Symes, Wendy, White, Caroline, Woodham, Adrine   +12 more
core   +1 more source

The CEA Second-Look Trial: a randomised controlled trial of carcinoembryonic antigen prompted reoperation for recurrent colorectal cancer [PDF]

, 2014
Objective In patients who have undergone a potentially curative resection of colorectal cancer, does a ‘second-look’ operation to resect recurrence, prompted by monthly monitoring of carcinoembryonic antigen, confer a survival benefit?Design A randomised
Bacon, Cochrane, Doshi, Ekman, Ellis, Embun, Fiorentino, Fiorentino, Fiorentino, Gill, Goldenberg, Grunhagen, Horton, Keep, Kraemer, Lennon, Levesque, Lewis, Loder, Mach, Mackay, Martin, Martin, Meeker, Moertel, Morris, Nicholson, Northover, Polk, Poston, Primrose, Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2, Rosen, Searle, Staab, Treasure, Treasure, Treasure, Treasure, Utley, Wangensteen, Welch   +41 more
core   +1 more source

Clinical Trial Registration and Reporting: Drug Therapy and Prevention of Cardiac-Related Infections

Frontiers in Pharmacology, 2019
Objective: Clinical trials are the source of evidence. ClinicalTrials.gov is valuable for analyzing current conditions. Until now, the state of drug interventions for heart infections is unknown.
Lin-Lu Ma, Lin-Lu Ma, Yang Qiu, Mei-Na Song, Yun Chen, Yun Chen, Jian-Xin Qu, Jian-Xin Qu, Bing-Hui Li, Ming-Juan Zhao, Ming-Juan Zhao, Xin-Can Liu, Xin-Can Liu   +12 more
doaj   +1 more source

Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. [PDF]

, 2012
BACKGROUND: Dengue is the most important vector-borne viral infection of man, with approximately 2 billion people living in areas at risk. Infection results in a range of manifestations from asymptomatic infection through to life-threatening shock and ...
Dung, Nguyen Thi Phuong, Farrar, Jeremy, Hien, Tran Tinh, Merson, Laura, Peeling, Rosanna, Simmons, Cameron, Tai, Luong Thi Hue, Truong, Nguyen Thanh, Van Hao, Nguyen, Van Vinh Chau, Nguyen, Whitehorn, James, Wills, Bridget, Wolbers, Marcel   +12 more
core   +1 more source

The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial [PDF]

, 2013
Background: Group-based social skills training (SST) has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD). To date, no sufficiently powered randomised controlled trial has been performed to establish
Bender, Stephan, Cholemkery, Hannah, Elsuni, Leyla, Freitag, Christine M., Kieser, Meinhard, Kroeger, Anne K., Kunz, Cornelia Ursula   +6 more
core   +1 more source

Standards for reporting interventions in clinical trials of cupping (STRICTOC): extending the CONSORT statement

Chinese Medicine, 2020
Background The standards for reporting interventions in clinical trials of cupping (STRICTOC), in the form of a checklist and explanations for users, were designed to improve reporting of cupping trials, particularly the interventions, and thereby ...
Xuan Zhang, Ran Tian, Wai Ching Lam, Yuting Duan, Fan Liu, Chen Zhao, Taixiang Wu, Hongcai Shang, Xudong Tang, Aiping Lyu, Zhaoxiang Bian   +10 more
doaj   +1 more source

Time to Publication for Randomized Clinical Trials Presented as Abstracts at Three Gastroenterology and Hepatology Conferences in 2017

Gastro Hep Advances, 2023
Background and Aims: Results of randomized clinical trials are often first presented as conference abstracts but these abstracts may be difficult to find, and trial results included in the abstract may not be followed by subsequent journal publications ...
Elizabeth C. Wright, Devika Kapuria, Gil Ben-Yakov, Disha Sharma, Dev Basu, Min Ho Cho, Tomilowo Abijo, Kenneth J. Wilkins   +7 more
doaj   +1 more source