Results 81 to 90 of about 926,305 (280)

Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]

, 2014
Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M, Gornbein, Jeffrey, Harper, Ronald, Meymandi, Sheba, Miller, Patrick R, Schrader, Lara, Soss, Jason   +6 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

The impact of training non-physician clinicians in Malawi on maternal and perinatal mortality : a cluster randomised controlled evaluation of the enhancing training and appropriate technologies for mothers and babies in Africa (ETATMBA) project [PDF]

, 2012
Background: Maternal mortality in much of sub-Saharan Africa is very high whereas there has been a steady decline in over the past 60 years in Europe. Perinatal mortality is 12 times higher than maternal mortality accounting for about 7 million neonatal
A Wilson, C McCord, C Pereira, C Pereira, C Pope, Chisale Mhango, D Ellard, David Davies, David Ellard, Doug Simkiss, E McAuliffe, F Mullan, Francis Kamwendo, G Chilopora, J Bryce, J Ritchie, Joseph Paul O’Hare, K Hill, Ministry of Health, National Statistical Office (NSO), and ICF Macro, Ngianga-bakwin Kandala, S Bergstrom, S Bradley, S Niermeyer, Siobhan Quenby, W Graham, W Graham, World Health Organization, UNICEF, UNFPA, and The World Bank   +27 more
core   +2 more sources

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

The Men's Safer Sex (MenSS) trial: protocol for a pilot randomised controlled trial of an interactive digital intervention to increase condom use in men [PDF]

, 2015
Introduction: Sexually transmitted infections (STI) are a major public health problem. Condoms provide effective protection but there are many barriers to use.
Anderson, Jane, Ang, Chee Siang, Bailey, Julia V., Dhanjal, Sacha, Estcourt, Claudia, Freemantle, Nick, Gerressu, Makeda, Hart, Graham, Hunter, Rachael, Michie, Susan, Murray, Elizabeth, Rait, Greta, Stephenson, Judith, Webster, Rosie   +13 more
core   +2 more sources

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Unreported links between trial registrations and published articles were identified using document similarity measures in a cross-sectional analysis of ClinicalTrials.gov

, 2018
Objectives: Trial registries can be used to measure reporting biases and support systematic reviews but 45% of registrations do not provide a link to the article reporting on the trial.
Bourgeois, Florence, Coiera, Enrico, Dunn, Adam G.   +2 more
core   +1 more source

Low dose aspirin in the prevention of recurrent spontaneous preterm labour - the APRIL study: A multicenter randomized placebo controlled trial [PDF]

, 2017
Background: Preterm birth (birth before 37 weeks of gestation) is a major problem in obstetrics and affects an estimated 15 million pregnancies worldwide annually.
Bekker, M.N. (Mireille), Bloemenkamp, K.W.M. (Kitty), Bosmans, J.E. (Judith), de Boer, M.A. (Marjon A.), Duvekot, J.J. (Hans), Franssen, M.T.M. (Maureen), Groot, C.J.M. (Christianne) de, Hemels, M.A.C. (Marieke A.C.), Kok, M. (Marjolein), Mol, B.W.J. (Ben), Naaktgeboren, C. (Christiana), Nijman, T.A.J. (Tobias A.J.), Oudijk, M.A. (Martijn), Post, J.A.M. (Joris) van der, Scheepers, H.C.J. (Hubertina), Sikkema, J.M. (J. Marko), Sueters, M. (Marieke), van Drongelen, J. (Joris), van Laar, J.O. (Judith O.), Visser, L. (Laura)   +19 more
core   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source