Results 151 to 160 of about 116,263,120 (276)

Radial Versus Femoral Access for Carotid Artery Stenting in Patients With Carotid Artery Stenosis: Protocol of the Multicenter RACE-CAS Randomized Trial. [PDF]

Stroke Vasc Interv Neurol
Liu R, Yuan K, Liu X, Sun W, Huang X, Wang H, Yi T, Liu X, Yin Q, Ye R, Ma M, Zhu W, Liu X.   +12 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

THE EFFECTIVENESS OF LEGAL REMEDIES FOR THE PROTECTION OF THE RIGHT TO TRIAL WITHIN A REASONABLE TIME IN THE CONTEXT OF THE ECHR PRACTICE: THE EXPERIENCE OF POLAND

Juridical scientific and electronic journal, 2021
D.S. Boichuk, Ya.I. Panaid
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Trial within a reasonable time in the practice of the European Court of Human Rights

Ovaj rad analizira razvoj prava na suđenje u razumnom roku u Republici Hrvatskoj od 1990. godine do danas. U uvodnom dijelu predstavljena je važnost pravodobnog suđenja kao temeljnog ljudskog prava. Razmatra se konceptualno razumijevanje razumnog roka te
Kiralj, Toni
core  

Does stereotactic ablative body radiotherapy (SABR) added to continued systemic therapy improve time to treatment failure compared with physician's choice of systemic therapy in oligoprogressive ER-positive, HER2-negative advanced breast cancer? Study protocol for a multicentre, randomised, open-label phase II trial in Australian tertiary cancer centres (AVATAR-II). [PDF]

BMJ Open
Connolly E, White M, Siva S, Bressel M, See A, Hunter K, Tan J, Panettieri V, Day D, Byrne K, McCartney A, Webber K, Woodford K, David S.   +13 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Lyophilised faecal microbiota transplantation capsules for intestinal multidrug-resistant organism decolonisation: protocol for a randomised, double-blind, placebo-controlled trial. [PDF]

BMJ Open
Rubinić I, Palčevski D, Rosović T, Antonić M, Skočibušić N, Cepanec I, Knežević Z, Šantić M, Hauser G, Vlahović-Palčevski V.   +9 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Influence of low-dose colchicine on coronary microcalcification activity in patients with diffuse coronary artery disease undergoing coronary artery bypass grafting: protocol for single-centre randomised open-label blinded-endpoint trial (the COL-CABG trial). [PDF]

BMJ Open
Gao M, Kong X, Xu X, Zhao W, Li Q, Gao J, Liu Y, Liu Y, Yu Y, Zhang X, Li H.   +10 more
europepmc   +1 more source