Results 231 to 240 of about 116,263,120 (276)

PROspective Prostate Cancer Infrastructure: study protocol for the ProPCI 'trials within cohorts' study. [PDF]

BMJ Open
Wissing RO, van Elst T, Sedelaar M, Smeenk RJ, van den Berg P, van Dodewaard-de Jong JM, Lont AP, Hendriks MP, Luijendijk-de Bruin D, van de Luijtgaarden ACM, Roelofs LAJ, Vis AN, Hoekstra RJ, Bloemendal HJ, van Basten JA, Mehra N.   +15 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Real-world data on aortic endografts: Gore Together aortic registry protocol. [PDF]

Front Cardiovasc Med
Yamanouchi D, Khashram M, Gable D, Milner R, Yeung KK, Resch TA, Böckler D, Delaney C, Azizzadeh A, Shimamura K, Qasabian R, Han S, Feito Y, Trimarchi S.   +13 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean Analgesia: A Randomized Controlled Trial. [PDF]

Drug Des Devel Ther
Xing B, Lu J, Wang C, Xin P, Han F.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Knee proprioception in children with spastic cerebral palsy: an observational study. [PDF]

BMC Pediatr
Ericson A, Bartonek Å, Luis I, Eriksson M, Lidbeck C.   +4 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Acceptability and Implementation of a Primary Care Health Check for Autistic People: Findings From Evaluation Questionnaires and Interviews. [PDF]

Autism
Merrick H, Taylor H, Ingham B, Finch T, Al-Ashmori S, Herrington R, Scarlett C, Buckley C, Cooper SA, Fernandez-Garcia C, Haining S, Lees R, Lennox N, Moss S, Nicholls T, Nicolaidis C, Osborne M, Raymaker DM, Robinson T, Urbanowicz A, Wason JM, Wilson C, Parr JR.   +22 more
europepmc   +1 more source

Carotid Revascularization in the Era of Modern Medical Therapy: Is Urgency Still Justified? [PDF]

Stroke Vasc Interv Neurol
De Louche CD, Davies AH.
europepmc   +1 more source