Results 181 to 190 of about 5,142 (225)
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Nephron, 1989
Triamterene (TA) is a mild 'potassium-sparing' diuretic usually employed in combination with other more potent diuretics in the treatment of hypertension. TA pharmacokinetics and pharmacodynamics in normal volunteers, elderly subjects and in patients with renal and hepatic dysfunction are reviewed.
Domenic A. Sica, Todd W.B. Gehr
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Triamterene (TA) is a mild 'potassium-sparing' diuretic usually employed in combination with other more potent diuretics in the treatment of hypertension. TA pharmacokinetics and pharmacodynamics in normal volunteers, elderly subjects and in patients with renal and hepatic dysfunction are reviewed.
Domenic A. Sica, Todd W.B. Gehr
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Journal of Urology, 1985
Triamterene therapy is an unusual cause of nephrolithiasis and, when this agent is found in a stone, generally it is deposited in minor amounts. We report a renal calculus consisting mostly of triamterene and its 2 major metabolites in a patient taking a triamterene-containing drug, and discuss some implications.
E S, Dickstein, W D, Loeser
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Triamterene therapy is an unusual cause of nephrolithiasis and, when this agent is found in a stone, generally it is deposited in minor amounts. We report a renal calculus consisting mostly of triamterene and its 2 major metabolites in a patient taking a triamterene-containing drug, and discuss some implications.
E S, Dickstein, W D, Loeser
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Calcified Tissue International, 1987
A constant composition method has been used to compare the effects of triamterene renal stone material, synthetic triamterene precipitates, and soluble triamterene on the nucleation and crystallization kinetics of calcium oxalate in aqueous solution in vitro.
George H. Nancollas, D.J. White
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A constant composition method has been used to compare the effects of triamterene renal stone material, synthetic triamterene precipitates, and soluble triamterene on the nucleation and crystallization kinetics of calcium oxalate in aqueous solution in vitro.
George H. Nancollas, D.J. White
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Military Medicine, 1989
A 59-year-old white male presented with a triamterene renal stone and pyelonephritis, requiring percutaneous lithotomy. A combination of hydrochlorothiazide and triamterene had been previously prescribed despite no history of hypokalemia. The indications for potassium replacement therapy and risks of triamterene nephrolithiasis are reviewed.
D P, Dooley, M E, Callsen, J A, Geiling
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A 59-year-old white male presented with a triamterene renal stone and pyelonephritis, requiring percutaneous lithotomy. A combination of hydrochlorothiazide and triamterene had been previously prescribed despite no history of hypokalemia. The indications for potassium replacement therapy and risks of triamterene nephrolithiasis are reviewed.
D P, Dooley, M E, Callsen, J A, Geiling
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Journal of Urology, 1982
AbstractThe frequency of hospitalization for renal stones was similar for recipients of triamterene, hydrochlorothiazide (alone), thyroid and diazepam among members of a large prepaid health maintenance organization. In 4 triamterene recipients in whom analysis of the stone was done no triamterene was found.
Hershel Jick +5 more
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AbstractThe frequency of hospitalization for renal stones was similar for recipients of triamterene, hydrochlorothiazide (alone), thyroid and diazepam among members of a large prepaid health maintenance organization. In 4 triamterene recipients in whom analysis of the stone was done no triamterene was found.
Hershel Jick +5 more
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Metabolic Fate and Solubility of Triamterene—Not an Explanation for Triamterene Nephrolithiasis
Journal of Pharmaceutical Sciences, 1986In an attempt to explain the triamterene stone diathesis, we studied the excretion and solubility of triamterene, 1, and its metabolite, the sulfate ester of the hydroxy derivative of triamterene, 3. The urinary excretion pattern and metabolism in stone formers was the same as in other chronic users of triamterene or healthy volunteers.
Fritz Sörgel +2 more
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Triamterene-Induced Nephrolithiasis
Annals of Internal Medicine, 1979Excerpt A patient passed kidney stones composed entirely of a mixture of triamterene and a metabolic product of triamterene.
Bruce Ettinger +3 more
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Triamterene Crystalline Nephropathy
American Journal of Kidney Diseases, 2014Medications can cause a tubulointerstitial insult leading to acute kidney injury through multiple mechanisms. Acute tubular injury, a dose-dependent process, occurs due to direct toxicity on tubular cells. Acute interstitial nephritis characterized by interstitial inflammation and tubulitis develops from drugs that incite an allergic reaction.
Dawn S. Milliner +3 more
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Clinical Pharmacology and Therapeutics, 1985
Earlier studies of triamterene (T) disposition in man have reported hydroxytriamterene (T-OH) and hydroxytriamterene sulfate (T-O-SO3H) conjugate to be the major metabolites. We describe T kinetics through use of an HPLC method and confirm that after hydroxylation, T is rapidly converted to T-O-SO3H.
Emil T Lin +3 more
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Earlier studies of triamterene (T) disposition in man have reported hydroxytriamterene (T-OH) and hydroxytriamterene sulfate (T-O-SO3H) conjugate to be the major metabolites. We describe T kinetics through use of an HPLC method and confirm that after hydroxylation, T is rapidly converted to T-O-SO3H.
Emil T Lin +3 more
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