Results 191 to 200 of about 5,142 (225)

Excretion of Triamterene and Its Metabolite in Triamterene Stone Patients

The Journal of Clinical Pharmacology, 1985
As triamterene users may form kidney stones containing deposits of triamterene and its metabolites, we studied urinary excretion to detect any altered metabolism of triamterene in these patients. We found no significant differences between patients and matched control subjects in total recovery, hourly excretion patterns, and concentrations of ...
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Drug Fever and Triamterene

Annals of Internal Medicine, 1987
Excerpt To the editor: Table 2 in the report by Mackowiak and Le-Maistre (1) on drug fever incorrectly shows triamterene as a drug used for its effects on the central nervous system; it is a diuret...
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Mechanism of Triamterene-Induced Megaloblastosis

Annals of Internal Medicine, 1970
Abstract A patient with cirrhosis of the liver who developed megaloblastosis despite normal serum and red cell folate levels after receiving conventional doses of triamterene for 2 weeks is describ...
Samuel Waxman, Jose J. Corcino, Victor Herbert   +2 more
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METABOLISM OF TRIAMTERENE IN THE RAT

Drug Metabolism and Disposition, 1975
The metabolism of 14C-triamterene (TA), 2,4,7-triamino-6-phenylpteridine, was investigated in rats. After administration of 14C-TA (2 mg/kg, sc), 45% and 50% of the total radioactivity was excreted in urine and feces, respectively, during 72 hr. 14C-TA and its metabolites were separated by paper chromatography and countercurrent distribution. Unchanged
S T, Kau, B V, Sastry, J D, Alvin, M T, Bush   +3 more
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Hyperkalemic Effects of Triamterene

Annals of Internal Medicine, 1966
Excerpt Triamterene (2,4,7-triamino-6-phenylpteridine),*a potassium-retaining diuretic, has been used since 1961 (1).
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Triamterene-Induced Nephrolithiasis

JAMA: The Journal of the American Medical Association, 1981
To the Editor.— We wish to report a case of triamterene-induced nephrolithiasis. Other cases have been published elsewhere. 1,2 Report of a Case.— A 44-year-old man was admitted with left ureteral colic. The family history was negative for kidney stone disease. Since June 1974, he had been receiving insulin for adult-onset diabetes.
Robert W. Grunberg, Samuel J. Silberg
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Triamterene and Renal Stone Formation

Journal of Urology, 1982
We investigated the influence of triamterene (TA), and its metabolites parahydroxytriamterene (PHTA), and parahydroxytriamterene sulfate (PHTAS) on the nucleation and crystal growth of calcium oxalate monohydrate (COM), in supersaturated solution at 37C using a new constant composition technique.
George H. Nancollas, D.J. White
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Physicochemical and Structural Studies of Triamterene

Journal of Pharmaceutical Sciences, 1989
It has been shown by several physicochemical techniques that the existence of different crystal forms of triamterene, as well as the crystalline products from different solvents with distinct differences in melting points, does not necessarily imply polymorphic crystal forms. The crystalline structure for triamterene is reported herein, revealing a N,N-
Olaf Dahl, G.J. Marek, Henrich H. Paradies, K. Hans Ziedrich   +3 more
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Triamterene-Induced Nephrolithiasis

Annals of Internal Medicine, 1980
Excerpt To the editor: I wish to report a case of triamterene-induced nephrolithias is similar to that described by Ettinger and associates (1) in the November issue.
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Triamterene Solubility and Metabolism are not Causative Factors of Triamterene Nephrolithiasis

1985
Although the risk of passing a kidney stone during triamterene therapy is not yet fully understood1,2 there is enough evidence to suggest that deposition of triamterene and other drugs in kidney stones is a frequent occurrence3. Since our initial report on the presence of triamterene in kidney stones, only a few studies have appeared on this topic and ...
Bruce Ettinger, P. O. Schwille, L. Z. Benet, F. sörgel   +3 more
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