Results 201 to 210 of about 5,142 (225)

Triamterene kinetics and dynamics in cirrhosis

Clinical Pharmacology and Therapeutics, 1984
Triamterene is extensively metabolized by the liver and undergoes important presystemic elimination in normal subjects after oral doses. We examined triamterene disposition in eight healthy controls and seven patients with cirrhosis and ascites. A specific and sensitive HPLC assay was used to measure concentrations of triamterene and of its major ...
F Rocheleau, G Raymond, J P Villeneuve
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Triamterene-Induced Pancytopaenia in Idiopathic Haemochromatosis

Acta Clinica Belgica, 1980
SummaryThe paper reports pancytopaenia induced by Triamterene in a patient with idiopathic haemochromatosis. Some aspects of the antifolate activity of Triamterene and folate metabolism in haemochromatosis are discussed.Severe haematological disturbances related to Triamterene administration in alcoholic cirrhosis have been reported (3–5).
Goldman, Michel, Zegers De Beyl, Diederik, Delwiche, Francis, Bellens, Roger   +3 more
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Spectrophotometric simultaneous determination of triamterene and hydrochlorothiazide in Triamterene-H tablets by multivariate calibration methods

Journal of Pharmaceutical and Biomedical Analysis, 2001
The multivariate calibration methods of partial least-square regression and principal component regression were applied for the simultaneous spectrophotometry determination of triamterene (TRM) and hydrochlorothiazide (HYD) in their mixtures. The parameters of the chemometric procedure were optimized, and the proposed methods were validated with ...
Amir Sarrafi, Kazem Kargosha
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Triamterene with Hydrochlorothiazide in the Treatment of Hypertension

JAMA: The Journal of the American Medical Association, 1963
Triamterene, a new potassium-sparing pteridine diuretic was found to have a weaker saluretic effect than the benzothiadiazines in nonedematous patients. However, a combination of 50 mg of triamterene plus 25 mg of hydrochlorothiazide, while continuing to prevent potassium loss, exhibited saluretic potency equivalent to 50 mg of hydrochlorothiazide ...
Edward D. Freis, William C. Heath
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Triamterene Nephrolithiasis: Renewed Attention is Warranted

Journal of Urology, 1990
Although triamterene has been known to contribute to urinary calculus formation, it has been presumed to be a rare phenomenon. Our review of stone analyses performed during the last decade by a single laboratory reveals an increasing incidence of triamterene stones. Awareness of the calculogenic potential of triamterene-containing medications should be
Edwin L. Prien, Richard K. Babayan, Michael C. Carr   +2 more
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OBSERVATIONS ON TRIAMTERENE—A NEW DIURETIC

Australasian Annals of Medicine, 1963
SUMMARYIn subjects without cedema, triamterene given orally caused increased urinary excretion of sodium and chloride, but not of potassium, in the 12 hours following administration, but continued administration produced no effect on the 24‐hour electrolyte excretion.In a short‐term trial, in which patients were treated for four‐day periods with ...
Barnett Aj, Brandstater M, Baumgarten A
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Distribution and Pharmacokinetics of Triamterene in Rats

Journal of Pharmaceutical Sciences, 1977
The tissue distribution of 14C-triamterene was examined in the fact. After intravenous administration of 14C-triamterene, high concentration ratios between tissues and blood were found in most tissues except the brain, fat, and testes. The maximal concentration of the drug was in the kidneys, liver, heart, lungs, and skeletal muscle within the first 20
B.V. Rama Sastry, Sen T. Kau
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Clinical trial of the diuretic triamterene

Irish Journal of Medical Science, 1965
In acute experiments Triamterene caused moderate diuresis and natriuresis, the onset of action being apparent at the end of 1 hour and lasting for 6 hours. Urinary potassium content was diminished. Urinary chloride and bicarbonate were increased. Urinary pH rose.
E. Bourke, M. Ryan, P. Keelan, T. B. Counihan, Isabella Farrell   +4 more
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Pharmacodynamics of basic triamterene derivatives.

Pharmaceutical research, 1986
Triamterene derivatives with a basic side chain and with an additional hydroxyl group in their side chain (hydroxy bases) were investigated for their effects on urine volume and electrolyte excretion in male Wistar rats. All basic derivatives enhance urine volume and sodium excretion.
H. Spahn, H. Priewer, Ernst Mutschler
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Photodermatitis from triamterene

Contact Dermatitis, 1987
L. Fernández de Cores, D. Mujñoz, G. Bernaola, E. Fernández, I. Leanizbarrutia   +4 more
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