Results 51 to 60 of about 899,728 (285)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Damage spreading in two dimensional geometrically frustrated lattices: the triangular and kagome anistropic Heisenberg model

, 2003
The technique of damage spreading is used to study the phase diagram of the easy axis anisotropic Heisenberg antiferromagnet on two geometrically frustrated lattices.
B W Southern, Barry J H, Chalker J T, Chandra P, Fazekas P, Hinrichsen H, Kano K, Kawamura H, Kawamura H, Kuroda A, Miyashita S, Olive J A, S Bekhechi, Southern B W, Stephan W, Stephenson J, Sütö A, Xu H-J   +17 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Bilangan Invers Dominasi Total Pada Triangular Snake Graph, Line Triangular Snake Graph, dan Shadow Triangular Snake Graph

Jambura Journal of Mathematics, 2022
Let G = (V(G), E(G)) be a connected graph, where V(G) is the set of vertices and E(G) is the set of edges. The set Dt(G) is called the total domination set in G if every vertex v 2 V(G) is adjacent to at least one vertex in Dt (G).
Nurhamzah Nurhamzah, Nilamsari Kusumastuti, Fransiskus Fran   +2 more
doaj   +1 more source

Form factors of the half-infinite XXZ spin chain with a triangular boundary

, 2014
The half-infinite XXZ spin chain with a triangular boundary is considered in the massive regime. Two integral representations of form factors of local operators are proposed using bosonization.
Baseilhac, P., Kojima, T.
core   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Fuzzy Triangular Aggregation Operators

International Journal of Mathematics and Mathematical Sciences, 2018
We present a new class of fuzzy aggregation operators that we call fuzzy triangular aggregation operators. To do so, we focus on the situation where the available information cannot be assessed with exact numbers and it is necessary to use another ...
Ulrich Florian Simo, Henri Gwét
doaj   +1 more source

Low-frequency triangular wave generator [PDF]

, 1971
Triangular waveform is generated by a combination of two integrated circuit operational amplifiers, one to produce square wave and other to integrate square wave and generate triangular ...
Thompson, J. P.
core   +1 more source