Results 341 to 350 of about 157,767 (395)

1,2,3‐Triazole hybrids as anticancer agents: A review

Archiv der Pharmazie, 2021
Despite the advancements in the development of anticancer agents, more effective and safer anticancer drugs still need to be developed as the current agents cause unwanted side effects and many patients have become drug resistant. 1,2,3‐Triazoles, due to
Mohammad Mahboob Alam
semanticscholar   +1 more source

A review on the biomedical efficacy of transition metal triazole compounds

Journal of coordination chemistry, 2022
From the apocalyptic era of antibiotic resistance, the scientific community around the world is engaged in designing and developing metal-based compounds to inhibit and control continuously rising microbial infections.
S. Sumrra, Wardha Zafar, Muhammad Imran, Z. Chohan   +3 more
semanticscholar   +1 more source

The 1,2,3-triazole ‘all-in-one’ ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool

Expert Opinion on Drug Discovery, 2022
Introduction The 1,2,3-triazole ring occupies an important space in medicinal chemistry due to its unique structural properties, synthetic versatility and pharmacological potential making it a critical scaffold.
Deniz Lengerli, Kübra İbiş, Yahya Nural, E. Banoglu   +3 more
semanticscholar   +1 more source

Influence of Phosphorus Doping on Triazole-Based g-C3N5 Nanosheets for Enhanced Photoelectrochemical and Photocatalytic Performance.

ACS Applied Materials and Interfaces, 2021
Triazole-based g-C3N5, a potential catalyst, has received little attention over the years. We prepared phosphorus-doped g-C3N5 with one triazole and two triazine units for the first time to investigate its photoelectrochemical (PEC) and photocatalytic ...
Chechia Hu, Yu-Hsuan Lin, Masaaki Yoshida, Shu Ashimura   +3 more
semanticscholar   +1 more source

The antibacterial activity of 1,2,3-triazole- and 1,2,4-triazole-containing hybrids against Staphylococcus aureus: An updated review (2020-present).

Current Topics in Medicinal Chemistry, 2021
Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic-resistant S. aureus strains, which pose potential causes of morbidity and mortality,
Jie Li, Junwei Zhang
semanticscholar   +1 more source

Triazole antifungals: A review

Drugs of Today, 2015
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward trend for numerous years. Despite advancements in antifungal medication, treatment in certain patients can still be difficult for reasons such as impaired organ function, limited administration routes or poor safety profiles of
Mehrnoosh Hashemzadeh, Lee Peyton, S Gallagher   +2 more
openaire   +3 more sources

Phototautomerism of triazolo-triazole scaffold

Journal of Molecular Structure, 2020
It is shown that 4-methyl-7-(4-hydroxyphenyl)-[1,2,4]-triazolo[3,2-c][1,2,4]triazole exhibits a rich photoinduced protolytic behavior: Förster cycle shows that the protonated nitrogen of the triazolo-triazole ring is a weak photoacid, with ?pKa?-3; furthermore, at moderately basic pH its deprotonated monoanion exhibits a long distance water mediated ...
Capobianco A., Di Donato M., Caruso T., Centore R., Lapini A., Manfredi C., Velardo A., Volino S., Peluso A.   +8 more
openaire   +6 more sources

Silylated Tetrazoles and Triazoles

Zeitschrift für anorganische und allgemeine Chemie, 2009
Abstract1‐Dimethysilyltetrazole (1) has been prepared from 1H‐tetrazole and chlorodimethylsilane in the presence of 2,6‐lutidine, bis(1‐tetrazolyl)dimethylsilane (2) from the reaction of 1H‐tetrazole, dimethyldichlorosilane and triethylamine and 5‐(trimethylsilylamino)‐1H‐tetrazole (3) from 5‐amino‐tetrazole monohydrate and hexamethyldisilazane.
Gronde, Ingo, Mitzel, Norbert W.
openaire   +2 more sources

1,2,3‐Triazole hybrids with anti‐HIV‐1 activity

Archiv der Pharmazie, 2020
The human immunodeficiency virus type 1 (HIV‐1) is the major etiological agent responsible for the acquired immunodeficiency syndrome (AIDS), which is a serious infectious disease and remains one of the most prevalent problems at present.
Lian-Shun Feng, Man-Jie Zheng, Feng Zhao, Duan Liu   +3 more
semanticscholar   +1 more source

Excitation Wavelength Dependent Fluorescence of an ESIPT Triazole Derivative for Amine Sensing and Anti-Counterfeiting Applications.

Angewandte Chemie, 2019
Excitation wavelength dependent (Ex-De) emission materials have potential applications in anti-counterfeiting labels and bioimaging. Nevertheless, few purely organic chromophores are used in these areas.
Yujian Zhang, Heyi Yang, Huili Ma, G. Bian, Qiguang Zang, Jingwei Sun, Cheng Zhang, Zhongfu An, W. Wong   +8 more
semanticscholar   +1 more source