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QSAR Prediction of Aquatic Toxicity of Triazoles and Benzo-Triazoles
2011Triazoles and benzo-triazoles (TAZ/BTAZ) are potentially hazardous chemicals that adversely affect humans and other non-target species, and are on the list of substances of very high concern (SVHC) in the European regulation of chemicals REACH. TAZ/BTAZ are synthetic molecules used in various industrial processes (to obtain pharmaceuticals and ...
CASSANI, STEFANO +5 more
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2008
This chapter provides a critical update on developments in the chemistry of 1,2,4-triazoles over the last decade. 1,2,4-Triazoles have remained the topic of much research, primarily due to their ubiquitous presence in many pharmaceutical agents and, more recently, in other functional materials with uses in engineering as corrosion inhibitors and in ...
N. Jennings, Anthony D.M. Curtis
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This chapter provides a critical update on developments in the chemistry of 1,2,4-triazoles over the last decade. 1,2,4-Triazoles have remained the topic of much research, primarily due to their ubiquitous presence in many pharmaceutical agents and, more recently, in other functional materials with uses in engineering as corrosion inhibitors and in ...
N. Jennings, Anthony D.M. Curtis
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Expedient Iron-Catalyzed C-H Allylation/Alkylation by Triazole Assistance with Ample Scope.
Angewandte Chemie, 2016Triazole assistance set the stage for a unified strategy for the iron-catalyzed C-H allylation of arenes, heteroarenes, and alkenes with ample scope. The versatile catalyst also proved competent for site-selective methylation, benzylation, and alkylation
G. Cera, T. Haven, L. Ackermann
semanticscholar +1 more source
Synthesis of 1-(1,2,4-triazol-3-yl)-1,2,3-triazoles
Chemistry of Heterocyclic Compounds, 19801-(1,2,4-Triazol-3-yl)-1,2,3-triazoles were obtained by 1,3-dipolar cycloaddition of 3-azido-1,2,4-triazole to acetylene derivatives.
T. F. Sharamet +3 more
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Coumarin–triazole Hybrids and Their Biological Activities
, 2018Hybridization is emerged as a promising strategy in the discovery of new drugs, especially these with complimentary activities and multiple pharmacological targets that are the potential weapons to prevent the drug resistance.
Yi‐Lei Fan, Xing Ke, Min Liu
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Tetrahedron Letters, 1969
Photolytic cleavage of vic-triazole ring when unsubstituted at N, finding phenylacetonitrile production ...
R. Selvarajan, J.H. Boyer
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Photolytic cleavage of vic-triazole ring when unsubstituted at N, finding phenylacetonitrile production ...
R. Selvarajan, J.H. Boyer
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A Recent Portrait of Bioactive Triazoles
Current Bioactive Compounds, 2010Scientists have extensively explored new synthetic routes in order to obtain 1,2,3- and 1,2,4-triazoles as they represent a very interesting class of compounds due to their wide range of biological activities such as antitumor, antiinflammatory, analgesic, antifungal, antibacterial, antiviral, etc.
PIBIRI, Ivana, BUSCEMI, Silvestre
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Voriconazole: A second-generation triazole
Drugs of Today, 2001Voriconazole, a derivative of fluconazole, is an antifungal triazole with expanded spectrum of activity against a variety of yeasts and filamentous fungi. It exhibits fungicidal activity against Aspergillus species. Preliminary data from animal models and clinical trials show promise in the treatment of candidiasis and aspergillosis.
Elias K. Manavathu +1 more
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Conversion of N-Sulfonyl Triazoles into Triazole-Fused Isoindolines [PDF]
Synfacts, 2019 Emma McInturff, Victor Snieckus
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