Results 51 to 60 of about 842,779 (245)

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Impact of valve repair on mild tricuspid insufficiency in rheumatic mitral surgery

, 2021
--------------e-pub(22.1.12 현재)-------------- Objective: Tricuspid valve repair for mild tricuspid regurgitation during rheumatic mitral valve surgery is controversial.
정지현, 김준범, 유재석, 김대희, 김상은, 김완기, 정성호, 이재원   +7 more
core   +2 more sources

Tricuspid valve surgery for acute infective endocarditis can be performed with very low operative mortalityCentral MessagePerspective

JTCVS Open
Objective: Tricuspid valve surgery historically has been perceived as having elevated operative risk, prompting the recent development of transcatheter therapies including aspiration vegetectomy for endocarditis.
Ali Darehzereshki, MD, J. Hunter Mehaffey, MD, MSc, J.W. Awori Hayanga, MD, MPH, Lawrence Wei, MD, Taylor D'etcheverry, PA-C, Luigi F. Lagazzi, MD, Vinay Badhwar, MD   +6 more
doaj   +1 more source

Reoperation for isolated rheumatic tricuspid regurgitation

Journal of Cardiothoracic Surgery, 2018
Background The reoperation for isolated tricuspid regurgitation in rheumatic population is rare and still unclear and controversial because of the rarity of publications.
Younes Moutakiallah, Mahdi Aithoussa, Noureddine Atmani, Aniss Seghrouchni, Azeddine Moujahid, Abdedaïm Hatim, Iliyasse Asfalou, Zouhair Lakhal, Abdelatif Boulahya   +8 more
doaj   +1 more source

Percutaneous Tricuspid Valve Repair

JACC: Case Reports, 2021
Two heart transplant patients aged 80 and 83 years with recurrent heart failure due to severe tricuspid regurgitation are reported. In view of their high perioperative risk, both patients underwent percutaneous transcatheter edge-to-edge tricuspid valve repair, and both experienced excellent technical success, with favorable 2-year clinical outcome ...
Roth, Eliane, Noll, Georg, Gämperli, Oliver, Wenaweser, Peter, Wyss, Christophe, Grünenfelder, Jürg, Corti, Roberto, Biaggi, Patric   +7 more
openaire   +2 more sources

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Transcatheter tricuspid valve repair in a patient with isolated functional tricuspid valve regurgitation [PDF]

European Heart Journal, 2015
A 60-year-old man was hospitalized with chronic right heart failure, ascites, and peripheral oedema. He had a history of ischaemic cardiomyopathy without need for revascularization, persistent atrial fibrillation, and renal failure. Echocardiography showed moderately reduced left ventricular ejection fraction of 35–40%, without relevant AV or MV ...
Malasa, Margarita, Werner, Nikos, Nickenig, Georg, Hammerstingl, Christoph   +3 more
openaire   +3 more sources

Tricuspid valve repair in corrected transposition with situs inversus

, 1997
A 31-year-old female presented with tricuspid valve insufficiency, atrial septal defect, pulmonary valve stenosis, and corrected transposition of the great arteries with situs inversus.
Alayunt E.A., Islamoglu F., Alat I., Atay Y.   +3 more
core   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Cardiac morphological and morphometric analysis of Ardea alba

The Anatomical Record, EarlyView.
Abstract Ardea alba (Linnaeus, 1758) is a widely distributed heron species whose cardiovascular morphology remains poorly described. This study aimed to characterize the cardiac morphology and morphometry of adult A. alba. Ten specimens were analyzed using radiographic, morphometric, histological, scanning electron microscopy, and three‐dimensional ...
Julia Vaz Feio, Max Alex Santos Ferreira, Elane Guerreiro Giese, Érika Branco, Antônio Basílio Guerreiro Junior, Ana Rita de Lima   +5 more
wiley   +1 more source