Results 91 to 100 of about 145,419 (376)
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju+7 more
wiley +1 more source
N-(2-Pyridylmethyleneamino)dehydroabietylamine
The title compound {systematic name: 1-[(1R,4aS,10aR)-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]-N-[(E)-2-pyridylmethyleneamino]methanamine}, C26H33N2, has been synthesized from dehydroabietylamine.
Yong Wu+4 more
doaj +1 more source
Total Synthesis and Structural Revision of (‐)‐Sodagnitin E
We report the total synthesis of malabaricane triterpene sodagnitin E, marking the first synthesis of any malabaricane natural product to date. The enantioselective synthesis of two key fragments, followed by their coupling via a Mukaiyama aldol reaction delivered the triterpene framework in a convergent synthesis.
Philipp Schoch, Tanja Gaich
wiley +1 more source
Tricyclic Antidepressants and Sudden Death
Two cases of sudden death in children treated with tricyclic antidepressants for psychiatric disorders are reported from the Children’s Hospital, Seattle, WA.
J Gordon Millichap
doaj +1 more source
Conservative management of low back pain [PDF]
Back pain is prevalent worldwide, but back pain disability has reached epidemic proportions in many industrialised societies. Few patients have serious medical pathology or direct neurological involvement requiring surgery.
De Souza, LH, Frank, AO
core
Enantioselective Total Synthesis of (–)-Myrifabral A and B [PDF]
A catalytic enantioselective approach to the Myrioneuron alkaloids (−)-myrifabral A and (−)-myrifabral B is described. The synthesis was enabled by a palladium-catalyzed enantioselective allylic alkylation, that generates the C(10) all-carbon quaternary ...
Bartberger, Michael D.+3 more
core
Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y+79 more
core +1 more source
In order to study the existence of best proximity points of a ( T ) $\left ( T\right ) $ condition satisfying mapping, we introduce a new interesting notion of triangular projection in geodesic metric spaces. Using the famous Schauder fixed point theorem,
Sabar Taoufik
doaj +1 more source
Considerations for the use of anesthesia in patients undergoing tricyclic antidepressant treatment
Patients undergoing tricyclic antidepressant treatment given anesthesia have experienced the hypotensive effects of both drugs. Traditionally it was recommended to suspend these drugs until two weeks before surgery; however, it is currently proposed that
Iván Hamyd Salazar Carrera
doaj +2 more sources
Cardiovascular Effects of Tricyclic Antidepressants
Twenty-four pediatric studies, published from various centers between 1967 and 1996, involving 730 children and adolescents treated with imipramine, amitryptiline, desipramine, or nortryptiline, were surveyed for cardiovascular side effects at the ...
J Gordon Millichap
doaj +1 more source