Results 101 to 110 of about 145,419 (376)

Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

open access: yesACS Combinatorial Science, 2012
The synthesis of a unique isoindoline- and tetrahydroisoquinoline (THIQ)-containing tricyclic sultam library, utilizing a Heck-aza-Michael (HaM) strategy is reported.
Qin Zang   +8 more
semanticscholar   +1 more source

Alterações eletrocardiográficas na intoxicação aguda por antidepressivo tricíclico e suas implicações clínicas

open access: yesMedicina, 2010
Introdução: A intoxicação aguda por antidepressivos tricíclicos é comum nas salas de emergência. Anormalidades no eletrocardiograma de 12 derivações (ECG) são associadas a este tipo de intoxicação, com implicações diagnósticas e prognósticas.
Carlos H. Miranda   +3 more
doaj   +1 more source

Reusable Selenenyl Iodide‐Initiated Cascade Cyclization of Polyenes with N‐terminating Groups

open access: yesChemistry – An Asian Journal, EarlyView.
A cascade cyclization of polyenes with N‑terminating groups, initiated by an isolable selenenyl iodide, was developed. The cavity‑shaped substituent stabilized both the selenenyl iodide and the selenenic acid generated via β‑selenoxide elimination, enabling the regeneration of selenenyl iodide.
Satoru Kuwano   +4 more
wiley   +1 more source

Graphs with 3-rainbow index $n-1$ and $n-2$ [PDF]

open access: yes, 2013
Let $G$ be a nontrivial connected graph with an edge-coloring $c:E(G)\rightarrow \{1,2,\ldots,q\},$ $q\in \mathbb{N}$, where adjacent edges may be colored the same. A tree $T$ in $G$ is a $rainbow tree$ if no two edges of $T$ receive the same color.
Li, Xueliang, Yang, Kang, Zhao, Yan
core  

Medications, epilepsy and climate change: Added layers of complexity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi   +2 more
wiley   +1 more source

The synergistic effect of anticholinergic burden and depression on fall risk in older persons

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Both anticholinergic burden (ACB) and depression are known to increase fall risk in older persons, next to increasing morbidity and mortality. However, the effect of depression on fall risk associated with ACB is unclear. This is relevant because several antidepressants have anticholinergic effects to some extent.
Raymond Salet   +7 more
wiley   +1 more source

Approach to the Core Structure of Signermycin B

open access: yesChemistryOpen
Among the natural tetramic acids with a decalinoyl part, signermycin B is unique because it contains a cis‐decalin. In this paper, we demonstrate that the cis‐decalin section of signermycin B can be accessed by an anionic oxy‐Cope rearrangement.
Dr. Khoa Linh Pham   +1 more
doaj   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

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