Results 181 to 190 of about 140,376 (301)

Urologic chronic pelvic pain syndrome 3‐year symptom trajectories: the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study

BJU International, Volume 137, Issue 2, Page 312-322, February 2026.
Objectives To characterise 3‐year pelvic pain and urinary symptom trajectories and to identify baseline factors associated with urologic chronic pelvic pain syndrome (UCPPS) improvement. Patients and Methods The Trans‐Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study was a multicentre, prospective cohort study
Catherine S. Bradley, Mengying You, Wensheng Guo, Niloofar Afari, Priyanka Gupta, Karl J. Kreder, John N. Krieger, H. Henry Lai, Susan K. Lutgendorf, Bruce D. Naliboff, Siobhan Sutcliffe, Frank Tu, David A. Williams, Tara McWilliams, Larissa Rodriguez, J. Richard Landis, for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network   +16 more
wiley   +1 more source

Rhodium- und Gold-katalysierte Cyclisierungsreaktionen zur Synthese B-Ring modifizierter Colchicinderivate und strukturell verwandter Verbindungen [PDF]

, 2009
Ritter, Stefanie
core  

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 310-320, February 2026.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano, Naoya Miyamoto, Kosuke Fujioka, Hiroki Toya, Juri Sakata, Hidetoshi Tokuyama   +5 more
wiley   +2 more sources

Impact of Cannabis Smoking on Multiple Sleep Latency Test Outcomes

Journal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT Our purpose was to evaluate how cannabis smoking influenced multiple sleep latency test (MSLT) outcomes. This was a retrospective study of all adults that had undergone a MSLT at St. Michael's Hospital (Toronto, Ontario, Canada) from 1 January 2008 until 31 December 2018.
Kosta Tzanis, Jenna Sykes, Clodagh M. Ryan, Nicholas T. Vozoris   +3 more
wiley   +1 more source

An organometallic approach to the synthesis of heteropolycyclic compounds from benzenes. [PDF]

Nat Commun
Siano P, Diment LA, Siela DJ, Ericson MN, McGraw M, Livaudais BF, Dickie DA, Harman WD.   +7 more
europepmc   +1 more source

Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

Discovery of Tricyclic Aromatic Polyketides Reveals Hidden Chain-Length Flexibility in Type II Polyketide Synthases. [PDF]

Int J Mol Sci
Liu Y, Wang L, Wang H, Zhu Y, Sun J, Ma B, Liu L, Bao X, Ren J, Fan K, Wang L, Li X, Pan G.   +12 more
europepmc   +1 more source

The Effect of Use of Tricyclic Antidepressants or Serotonin-Norepinephrine Reuptake Inhibitors Versus Selective Serotonin Reuptake Inhibitors on the Risk of Urinary Tract Infection Among People With Multiple Sclerosis: A Nested Case-Control Study. [PDF]

Pharmacoepidemiol Drug Saf
Leung MWY, van de Garde EMW, Uitdehaag BMJ, Souverein PC, Klungel OH, Bazelier MT.   +5 more
europepmc   +1 more source

Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial.

Journal of the American Medical Association (JAMA), 2001
K. Holroyd, Francis J. O’Donnell, M. Stensland, G. Cordingley, Bruce W. Carlson   +4 more
semanticscholar   +1 more source