Selektive Metallierung von BicycIo[3.2.1]octa-2,6-dien, II Distannylierte Derivate und stannylierte tricyclische Sekundärprodukte / Selective Metalation of Bicyclo[3.2.1]octa-2,6-diene, II Distannylated Derivatives and Stannylated Tricyclic Secondary Products [PDF]
, 1988 Norbert Hertkorn, Frank H. Köhler
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Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Mechanistic Insights and Therapeutic Potential of the Antidepressant Amitriptyline against <i>Leishmania (Leishmania) amazonensis</i>. [PDF]
ACS OmegaMesquita JT +3 more
europepmc +1 more source
Behavioral-pharmacological studies on doxepin, a tricyclic psychotropic agent
, 1972 Sakutaro Tadokoro
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Inhibitory actions of amoxapine, a tricyclic antidepressant agent, on electrophysiological properties of mammalian isolated cardiac preparations [PDF]
, 1988 Toru Kinugawa +2 more
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Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, EarlyView.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
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Application of machine learning in forensic geochemistry using presalt oil samples from the Santos basin. [PDF]
Sci RepSilva GMA +8 more
europepmc +1 more source
Effects of tricyclic antidepressants on tetrabenazine-induced depletion of brain monoamines in rats
, 1979 Toshio Yoshizaki, Kanya Tonda
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Structure‐based discovery of thiamine uptake inhibitors
British Journal of Pharmacology, EarlyView.Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel +2 more
wiley +1 more source
Therapeutic Potential of Tricyclic Pyridazinone-Based Molecules: An Overview. [PDF]
Int J Mol SciAsproni B +6 more
europepmc +1 more source