Results 11 to 20 of about 140,295 (222)
Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter
The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides c[WR]4 and c[WR]5 consisting of alternate arginine and tryptophan residues as nuclear ...
Sumit Kumar +5 more
doaj +1 more source
Eight cuttings samples were obtained from Sargelu and Kurrachine formations in different wells at different depths to detect steranes and triterpanes biomarkers as an indicator of the depositional environments and thermal maturity of organic matter. This
Al-Dolaimy, Arwa
doaj +1 more source
Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]
Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie +9 more
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Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J. +39 more
core +3 more sources
Fused Tricyclic Guanidine Alkaloids: Insights into Their Structure, Synthesis and Bioactivity
A marine natural product possesses a diverse and unique scaffold that contributes to a vast array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine natural products.
Nur Zahirah Abd Rani +4 more
doaj +1 more source
Six regioisomers associated with the tricyclic core of thiaplakortones A–D have been synthesized. Reaction of 1H-indole-4,7-dione and 1-tosyl-1H-indole-4,7-dione with 2-aminoethanesulfinic acid afforded a regioisomeric series, which was subsequently ...
Brett D. Schwartz +5 more
doaj +1 more source
Path energy of two kinds of special tricyclic graphs
Aiming at the problem that there are many kinds of tricyclic graphs and the complexity of path matrix is high, the path energy of two kinds of tricyclic graphs with or without pendant vertices was studied by means of matrix analysis, the existence ...
Wenjing LI, Yanling SHAO
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Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
Hitting times for random walks on tricyclic graphs
Let G be a simple connected graph and [Formula: see text] Let [Formula: see text] be the expected hitting time from x to y in G and [Formula: see text] be the hitting time of G, where [Formula: see text] A tricyclic graph is a simple connected graph that
Xiao-Min Zhu, Xu Yang
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Study of cascade ring-closing metathesis reactions en route to an advanced intermediate of Taxol [PDF]
A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features the tricyclic core and the required oxygen substituents at C1, C2, C7, C10 and C13. The key step, a ring-closing dienyne metathesis (RCDEYM) reaction, has
Letort, Aurélien +2 more
core +1 more source

