Results 61 to 70 of about 145,419 (376)
Tandem ring-closing metathesis reaction with a ruthenium catalyst containing a N-heterocyclic ligand [PDF]
, 2001 The highly active catalyst 2 was used in tandem RCM to make molecules with various ring systems containing α,β-unsaturated carbonyl ...
Choi, Tae-Lim, Grubbs, Robert H.
core +1 more source
Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]
, 2020 Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core +1 more source
Aggregate, EarlyView.A domino reaction leading to the novel heterocyclic aggregate 2,9‐dihydrobenzo[b]cyclopenta[e][1,4]thiazine has been developed, with its mechanism elucidated by crystallography and ESI‐MS to reveal a 15‐step reaction sequence (the longest reported to date) involving intermolecular C‐C coupling and intramolecular expansion.
Kai‐Bin Chen +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Two solvated hydrogen‐bonded organic frameworks (HOFs) based on tetraazaanthraquinone and anthraquinone were found to undergo quasi single‐crystal‐to‐single‐crystal transformations through hydrogen‐bond cleavage and re‐formation. These transformations induced crystal crack propagations, and molecular‐level correlations between the structural ...
Haruka Kubo +2 more
wiley +2 more sources
Molecules, 2000 Reaction of enone (11) with the bifunctional Grignard reagent (7) in the presence of copper(I) bromide – dimethyl sulfide, followed by intramolecular alkylation of the resultant chloroketone (15) gave the tricyclic ketone (12). The tricyclic ketone (
Veljko Dragojlovic
doaj +1 more source
Cancer Discovery, 2013 UNLABELLED Small cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of lung cancer with high mortality. We used a systematic drug repositioning bioinformatics approach querying a large compendium of gene expression profiles to identify ...
N. Jahchan +16 more
semanticscholar +1 more source
THE RADIOIMMUNOASSAY OF TRICYCLIC ANTIDEPRESSANTS [PDF]
British Journal of Clinical Pharmacology, 1976 An antiserum to nortriptyline has been produced in a sheep against a nortriptyline‐bovine serum albumin conjugate. The conjugate was prepared using the reagent N‐(4‐bromobutyl) phthalimide followed by a carbodiimide reaction to link the hapten to the carrier protein.
G W Aherne, E. M. Piall, Vincent Marks
openaire +2 more sources
Sulfenamides as flame retardants [PDF]
, 2015 FIELD OF THE INVENTION The present invention is in the field of flame retardants and relates to use of sulfenamides as flame retardants, in particular in polymeric sub ...
Aubert, Melanie +3 more
core
Asian Journal of Organic Chemistry, EarlyView.A straightforward method for constructing a tetrasubstituted carbon center through the in situ formation of 3‐methyleneisoindolinones as reactive intermediates has been developed. This process involves an acid‐catalyzed Meyer‐Schuster rearrangement of isoindolinone‐based propargylic alcohols, followed by an intermolecular Friedel‐Crafts alkylation ...
Arben Beriša +4 more
wiley +1 more source
Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons
Frontiers in Physiology, 2014 Amitriptyline, a tricyclic antidepressant, has been used in the clinic to treat a number of disorders, in particular major depression and neuropathic pain.
Nadine Beckmann +4 more
semanticscholar +1 more source