British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 612-618, February 2026.MicroRNA‐122 (miR‐122) is a sensitive biomarker for paracetamol‐induced liver injury. This study assessed the diagnostic performance of dynamic chemical labelling (DCL) combined with an immunoassay platform to quantify miR‐122 in human serum, as a proof‐of‐concept for hospital use.
Samar Alzeer +9 more
wiley +1 more source
Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson's disease. [PDF]
Psychopharmacology (Berl), 2022 Kamińska K +3 more
europepmc +1 more source
From Struggling (With) Screening Tests to Mouse Models of Depression‐Relevant Neurobehavioral States
Current Protocols, Volume 6, Issue 2, February 2026.Abstract A major, serendipitous psychiatric discovery is monoamine‐transporter reuptake inhibition as an antidepressant mechanism of action. Chronic treatment with such antidepressants is efficacious, with onset requiring 1‐2 weeks, in many but by no means all patients with major depressive or another stress‐related neuropsychiatric disorder.
Christopher R. Pryce
wiley +1 more source
Inhibition of Neutrophil Secretion Upon Adhesion as a Basis for the Anti-Inflammatory Effect of the Tricyclic Antidepressant Imipramine. [PDF]
Front Pharmacol, 2021 Galkina SI +8 more
europepmc +1 more source
Tricyclic antidepressant pharmacology and therapeutic drug interactions updated
British Journal of Pharmacology, 2007 P. Gillman
semanticscholar +1 more source
Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)
European Journal of Pain, Volume 30, Issue 2, February 2026.ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo +8 more
wiley +1 more source
Valutazione dei livelli di BDNF ematico in uno studio di follow-up su pazienti con depressione maggiore [PDF]
, 2005 Il fattore neurotrofico cervello-derivato (BDNF) è, tra i membri della famiglia delle neurotrofine, quello che mostra l'espressione più diffusa nel cervello del mammifero adulto e in fase di sviluppo.
Scatena, Alessia
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Food Science &Nutrition, Volume 14, Issue 2, February 2026.Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech +8 more
wiley +1 more source
Russian Open Medical Journal, 2013 Aim – This study was aimed to investigate the pattern of antidepressant drugs prescription among general practitioners and psychiatrists of Kerman/Iran with the goal of preventing irrational drug use.
Hamid Reza Motevallyzadeh +3 more
doaj
MEDICATION USE AND FALLS IN OLDER ADULTS: A PHARMACOEPIDEMIOLOGIC APPROACH [PDF]
, 2014 More than one-third of community-dwelling older adults fall each year. Falling is classified as a geriatric syndrome which has multiple contributing factors and an interaction between chronic predisposing diseases and impairments and acute precipitating ...
Castle, Nicholas +5 more
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