Results 141 to 150 of about 176,899 (274)

Predicting Pharmacological Treatment Response in Migraine Using AI/ML: A Scoping Review of the Evidence and Future Directions

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.
ABSTRACT The treatment of migraine is hampered by inter‐individual variability, leading to an inefficient “trial and error” approach. Artificial intelligence (AI) and machine learning (ML) offer a path towards precision medicine by predicting therapeutic outcomes.
Martina Giacon, Salvatore Terrazzino
wiley   +1 more source

The Comparison of Efficacy of Tricyclic Antidepressant with and without Non Steroidal Anti Inflammatory Drugs in Chronic Low Back Pain

پزشکی بالینی ابن سینا, 2007
Introduction & Objectives: Low back pain (LBP) is one of common medical problems with several accepted medical modalities such as drugs, physiotherapy, surgery, etc.
Alireza Yavarikia
doaj  

Genetic ablation of the isoform γ of PI3K decreases antidepressant efficacy of ketamine in male mice

IBRO Neuroscience Reports
About one-third of major depressive disorder (MDD) patients demonstrate unresponsiveness to classic antidepressants, and even the clinical efficacy of fast-acting drugs such as ketamine varies significantly among patients with treatment-resistant ...
Gabriela N. Vaz, Flávia C. Turcato, Isabel A.V. Lima, Franciele F. Scarante, Melissa R. Araújo, Tamires A.V. Brigante, Livia C.M. Rodrigues, Francisco S. Guimarães, Jaime E.C. Hallak, Jose A. Crippa, Antonio L. Teixeira, Antonio C.P. de Oliveira, Alline Cristina Campos   +12 more
doaj   +1 more source

Veno-arterial extracorporeal membrane oxygenation and targeted temperature management in tricyclic antidepressant-induced cardiac arrest: A case report and literature review. [PDF]

Medicine (Baltimore), 2021
Ikejiri K, Akama Y, Ieki Y, Kawamoto E, Suzuki K, Yokoyama K, Ishikura K, Imai H.   +7 more
europepmc   +1 more source

Two Cases of Refractory Nocturnal Enuresis Effectively Treated With Kampo Medicine: A Case Series in Pediatric and Adult Patients

Traditional &Kampo Medicine, Volume 13, Issue 1, April 2026.
Kazuyoshi Johnin, Yuri Mori, Shigehisa Kubota, Kenichi Kobayashi, Tetsuya Yoshida, Susumu Kageyama   +5 more
wiley   +1 more source

Duplicate Prescription Patterns in Patients With Substance Use Disorders

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross‐sectional
Johannes Heck, Benjamin Krichevsky, Martin Schulze Westhoff, Konstantin Fritz Jendretzky, Martin Klietz, Stephan Greten, Alexander Glahn, Stefan Bleich, Sebastian Schröder   +8 more
wiley   +1 more source

Characterization of tricyclic anti-depressant drugs efficacy via topological indices

Scientific Reports
Within the context of graph theory, a topological index serves as a numerical descriptor that encapsulates the physicochemical properties of a chemical graph.
Simran Kour, J. Ravi Sankar
doaj   +1 more source

The Risk Factors and Mortality Among Patients With Different Combination Patterns of Opioids and Benzodiazepines: A Retrospective Study

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT The concurrent use of opioids and benzodiazepines (BZDs) has raised safety concerns due to increased risks of respiratory depression and death. To evaluate mortality risks linked to different patterns of co‐prescription, we conducted a retrospective cohort study using data from a private hospital system between 2008 and 2018.
Fang‐Yu Su, Ming‐Che Tsai, Yee‐Yung Ng, Shiao‐Chi Wu   +3 more
wiley   +1 more source

Clinical presentation and management of repetitive circling behaviour in a working cocker spaniel secondary to meningoencephalomyelitis of unknown aetiology

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 3‐year‐old, entire, male cocker spaniel presented for behavioural assessment following a 2.5‐year history of compulsive circling to the right‐hand side. It was previously diagnosed with meningomyelitis of unknown aetiology, following an acute onset of blindness in the left eye and decreased postural reactions.
Emma Gatehouse, Vera Pisco
wiley   +1 more source

Urologic chronic pelvic pain syndrome 3‐year symptom trajectories: the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study

BJU International, Volume 137, Issue 2, Page 312-322, February 2026.
Objectives To characterise 3‐year pelvic pain and urinary symptom trajectories and to identify baseline factors associated with urologic chronic pelvic pain syndrome (UCPPS) improvement. Patients and Methods The Trans‐Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study was a multicentre, prospective cohort study
Catherine S. Bradley, Mengying You, Wensheng Guo, Niloofar Afari, Priyanka Gupta, Karl J. Kreder, John N. Krieger, H. Henry Lai, Susan K. Lutgendorf, Bruce D. Naliboff, Siobhan Sutcliffe, Frank Tu, David A. Williams, Tara McWilliams, Larissa Rodriguez, J. Richard Landis, for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network   +16 more
wiley   +1 more source