Results 261 to 270 of about 157,293 (343)

Tricyclic Antidepressant Overdose in a Toddler Treated With Intravenous Lipid Emulsion

Pediatrics, 2011
We report a case that involves the use of intravenous lipid emulsion as an antidote for a drug overdose involving a 20-month-old girl who had ingested a potentially lethal amount of the tricyclic antidepressant (TCA) dothiepin.
D. Hendron, G. Menagh, E. Sandilands, D. Scullion   +3 more
semanticscholar   +1 more source

Tricyclic Antidepressant Agranulocytosis

The Canadian Journal of Psychiatry, 1986
Severe neutropenia is an unusual complication of antidepressant therapy. We report a case of agranulocytosis due to clomipramine, and discuss principles of management.
D S Gravenor, G Blake, J R Leclerc
openaire   +3 more sources

Tricyclic Antidepressant Overdose

Pediatric Clinics of North America, 1986
Overdose of a tricyclic antidepressant is a serious and all-too-frequent occurrence. The diagnosis must be considered in known or suspected overdoses, and signs such as a dry axilla, tachycardia, and wide QRS must be specifically sought. Management depends upon support of vital functions and a thorough understanding of the pharmacology of the drug ...
P.D. Walson, N.J. Braden, J.E. Jackson
openaire   +3 more sources

Clinical aspects of tricyclic antidepressant poisoning.

Acta Medica Scandinavica, 2009
Self-poisoning with antidepressant drugs was studied retrospectively in 225 patients admitted to an intensive care unit. Amitriptyline accounted for the overwhelming majority of cases (70%); 106 patients (47%) had taken two or more drugs, in 81 patients (
B. Hultén, A. Heath
semanticscholar   +1 more source

Tricyclic antidepressants and delirium

Journal of Clinical Psychopharmacology, 1983
Some patients who take tricyclic antidepressants (TCAs) develop delirium. Charts were reviewed of 125 inpatients whose TCA plasma levels had been assayed. Delirium was documented in 10 cases. The occurrence of delirium was statistically related to age, race, and loge plasma TCA levels.
Keith Isenberg, David K. Zucker, Richard L. Livingston, Richard D. Wetzel   +3 more
openaire   +3 more sources

Evaluation of risk factors for elevated tricyclic antidepressant plasma concentrations

Pharmacoepidemiology and Drug Safety, 2009
To quantify the effect of clinical and demographic factors on the risk of elevated and toxic tricyclic antidepressant (TCA) plasma concentrations (Cp) and to describe the rates of elevated and toxic TCA Cp.
S. Billups, T. Delate, D. Dugan
semanticscholar   +1 more source

Inhibition of Astroglial Inwardly Rectifying Kir4.1 Channels by a Tricyclic Antidepressant, Nortriptyline

Journal of Pharmacology and Experimental Therapeutics, 2007
The inwardly rectifying K+ (Kir) channel Kir4.1 is responsible for astroglial K+ buffering. We examined the effects of nortriptyline, a tricyclic antidepressant (TCA), on Kir4.1 channel currents heterologously expressed in HEK293T cells, using a whole ...
S. Su, Y. Ohno, Christoph Lossin, H. Hibino, A. Inanobe, Y. Kurachi   +5 more
semanticscholar   +1 more source

Lithium and Tricyclic Antidepressants

Psychiatric Clinics of North America, 1992
Pharmacokinetic studies of lithium and tricyclic antidepressants (TCAs) in children and adolescents report similarities to adults with respect to a wide interindividual genetic variation in the rate of elimination and with regard to the linear nature of the system.
Harriet H. Fetner, Barbara Geller
openaire   +3 more sources

A Preliminary Study of Tricyclic Antidepressant (TCA) Ovine FAB for TCA Toxicity

Clinical toxicology, 2006
Background. Animal studies suggest that tricyclic antidepressant antibody fragments (TCA Fab) may be a useful therapy for tricyclic antidepressant poisoning.
K. Heard, R. Dart, G. Bogdan, G. O’Malley, K. Burkhart, J. Donovan, S. Ward   +6 more
semanticscholar   +1 more source

Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature.

American Journal of Psychiatry, 2001
OBJECTIVE The delayed onset of therapeutic response to antidepressants remains a major problem in the treatment of depression. Among the strategies to accelerate response to treatment, the early addition of thyroid hormone to antidepressants has been ...
L. Altshuler, Michael Bauer, M. Frye, M. Gitlin, J. Mintz, M. Szuba, Kristin L. Leight, P. Whybrow   +7 more
semanticscholar   +1 more source