Results 281 to 290 of about 157,293 (343)
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Tricyclic Antidepressants and Children

The Nurse Practitioner, 1991
Tricyclic antidepressants have been used in the treatment of certain childhood disorders for more than 20 years, and indications for their use in the pediatric population are increasing. Research supports the use of tricyclics for preadolescent children as adjunctive therapy for major depression, attention deficit hyperactivity disorder, enuresis, tic ...
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Tricyclic Antidepressants-Reply

JAMA: The Journal of the American Medical Association, 1979
In Reply.— Dr Coodley addresses several important issues, two of which we will address. Although we agree that there are subjective side effects at the 75-mg dose of imipramine, in studies of steady-state plasma levels of tricyclic antidepressants, loading doses of 100 mg of imipramine are routinely administered to naive subjects without side effects,
Neal R. Cutler, Jon F. Heiser
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Prediction of Treatment Response in Geriatric Depression From Baseline Folate Level: Interaction With an SSRI or a Tricyclic Antidepressant

Journal of Clinical Psychopharmacology, 2003
Depressed geriatric patients have lower levels of folate (FOL) than controls. Also, FOL supplement can reduce depressive morbidity. One hypothesis consistent with this is that FOL deficiency causes a lowering of CNS serotonin that contributes to ...
M. Alpert, Raul R. Silva, E. Pouget
semanticscholar   +1 more source

Serial electrocardiogram changes in acute tricyclic antidepressant overdoses.

Critical Care Medicine, 1997
OBJECTIVES To describe the changes over time of the QRS interval and terminal 40-msec QRS frontal axis (T40-ms) in patients with acute tricyclic antidepressant poisoning, to identify clinical factors and treatment associated with these changes, and to ...
Erica L. Liebelt   +3 more
semanticscholar   +1 more source

Tricyclic Antidepressants and Lithium

Clinics in Laboratory Medicine, 1981
Although difficulty in correlating plasma levels of tricyclic antidepressants with therapeutic outcome has been reported, therapeutic monitoring can be helpful in the management of selected depressed patients. The greater toxic potential of lithium is a pressing and clear indication for therapeutic monitoring in manic patients.
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The Tricyclic Antidepressants

1986
Depression is a common, albeit probably underdiagnosed and undertreated, disorder of late adult life.1 This illness affects an estimated 7–11% of individuals over 65 years of age.2 When depression is properly diagnosed and treated, the prognosis for recovery is good, even in older patients. Pharmacotherapy remains the mainstay of treatment of affective
Matthew V. Rudorfer, William Z. Potter
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The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts.

Biological Chemistry Hoppe-Seyler, 1994
The effect of the tricyclic antidepressant desipramine on the processing of lysosomal sphingomyelinase (EC 3.1.4.12) was investigated by pulse-chase studies on [35S]methionine labeled cultured human skin fibroblasts.
R. Hurwitz, K. Ferlinz, K. Sandhoff
semanticscholar   +1 more source

The Efficacy of Tricyclic Antidepressants

JAMA: The Journal of the American Medical Association, 1988
To the Editor. — In the July 15 issue of JAMA , Dr Renshaw 1 presents a case discussion of the use of a tricyclic antidepressant in treating a young woman with interstitial cystitis and depression. While I found the case interesting, I take issue with the assumption that the presence of anticholinergic side effects means a therapeutic blood level has ...
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Tricyclic Antidepressant Cardiotoxicity

JAMA: The Journal of the American Medical Association, 1977
To the Editor.— The article by Robinson and Barker (236:2089, 1976) regarding tricyclic antidepressant (TCA) toxicity has its good and bad features. The good is that the Food and Drug Administration and its advisors are continuing to present their data and views in a general scientific forum.
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Physostigmine salicylate in the treatment of tricyclic antidepressant overdosage.

Journal of the American Medical Association (JAMA), 1975
Following intravenous administration of physostigmine salicylate for tricyclic antidepressant poisoning in 21 patients, convulsions occurred in two patients, and severe cholinergic manifestations occurred in two others.
R. Newton
semanticscholar   +1 more source

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