Results 51 to 60 of about 157,293 (343)

χ-Conotoxin and Tricyclic Antidepressant Interactions at the Norepinephrine Transporter Define a New Transporter Model*

open access: yesJournal of Biological Chemistry, 2007
Monoamine neurotransmitter transporters for norepinephrine (NE), dopamine and serotonin are important targets for antidepressants and analgesics. The conopeptide χ-MrIA is a noncompetitive and highly selective inhibitor of the NE transporter (NET) and is
F. A. Paczkowski   +3 more
semanticscholar   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund   +5 more
wiley   +1 more source

Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice

open access: yesJournal of Mind and Medical Sciences, 2019
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Cornel Chiriță   +8 more
doaj   +1 more source

Antidepressant efficacy and side effect burden: an updated guide for clinicians

open access: yesDrugs in Context, 2020
Antidepressant treatment has been evolving and changing since the 1950s following the discovery of the classic antidepressant treatments including tricyclic antidepressants and monoamine oxidase inhibitors.
Tatum Kutzer   +4 more
doaj   +1 more source

Antidepressants and Gastric Cancer: A Nationwide Population-Based Nested Case-Control Study. [PDF]

open access: yesPLoS ONE, 2015
To our knowledge, no epidemiological study has reported on whether an association between antidepressant exposure and gastric cancer exists. Herein, we aim to investigate the possible association between antidepressant exposure and gastric cancer ...
Yi-Hsuan Hsieh   +7 more
doaj   +1 more source

Structure, stability and electronic properties of tricycle type graphane [PDF]

open access: yes, 2012
We propose a new allotrope of graphane, named as tricycle graphane,with a 4up/2down UUUDUD hydrogenation in each hexagonal carbon ring,which is different from previously proposed allotropes with UUDUUD(boat-1) and UUUUDD (boat-2) types of hydrogenation. Its stability and electronic structures are systematically studied using first-principles method. We
arxiv   +1 more source

Estimation of the marginal effect of antidepressants on body mass index under confounding and endogenous covariate-driven monitoring times [PDF]

open access: yesarXiv, 2021
In studying the marginal effect of antidepressants on body mass index using electronic health records data, we face several challenges. Patients' characteristics can affect the exposure (confounding) as well as the timing of routine visits (measurement process), and those characteristics may be altered following a visit which can create dependencies ...
arxiv  

Differential impact on isolated REM sleep without atonia by varying antidepressant therapies

open access: yesJournal of Affective Disorders Reports, 2020
Background: REM sleep without atonia (RSWA) is characterized by increased phasic or tonic muscle activity in electromyography channels during polysomnography and usually causes REM sleep behavior disorder, but RSWA also exists within healthy populations ...
John Feemster   +2 more
doaj  

Progress of non‐motor symptoms in early‐onset Parkinson's disease

open access: yesIbrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang   +5 more
wiley   +1 more source

Mania induced by opipramol

open access: yesIndian Journal of Psychological Medicine, 2015
Antidepressants have propensity to induce manic switch in patients with bipolar disorder. Opipramol is an atypical anxiolytic and antidepressant drug which predominantly acts on sigma receptors.
Kazhungil Firoz   +4 more
doaj   +1 more source

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