Results 101 to 110 of about 73,031 (218)

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan, Sanya Verma, Hannah Yeomans, Karen Bau, Caitlin Doyle, Monica S. Cooper, David J. Amor, Carolyn Berryman, Adrienne Harvey   +8 more
wiley   +1 more source

Academic‐Year Differences in Dental Students' Knowledge of Non‐Ionising Imaging: MRI‐Related Dental Material Safety and Ultrasonography

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Non‐ionising imaging is increasingly relevant to dental education, but students may not develop operational knowledge of magnetic resonance imaging (MRI)‐related dental material safety or dentomaxillofacial ultrasonography.
Alperen Tekin, Bengisu Deveci, Gökhan Tekin   +2 more
wiley   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

Headache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

Single-Cell Profiling Identifies Glial Transcriptional Remodeling in the Trigeminal Ganglion After Corneal Injury. [PDF]

Glia
Woodward AM, Martinez-Carrasco R, Argüeso P.   +2 more
europepmc   +1 more source

Opioid use, disability, and patient‐reported cognitive impairment in migraine: Multi‐country results from the Chronic Migraine Epidemiology and Outcomes—International Study

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Opioids are widely used to treat migraine despite being contrary to clinical guidelines. In the Chronic Migraine Epidemiology and Outcomes–International (CaMEO‐I) Study, a large, international survey of people with migraine, opioid users were more likely than nonusers to experience moderate or severe migraine‐related disability ...
Elizabeth Leroux, Dawn C. Buse, Michel Lanteri‐Minet, Fumihiko Sakai, Manjit Matharu, Zaza Katsarava, Kristina M. Fanning, Karen Carr, Nicole Naccara, Janette Contreras‐De Lama, Richard B. Lipton   +10 more
wiley   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson, D. Edwards, Q. Vuong, I. Obara   +3 more
wiley   +1 more source

Effect of Repeated Pulsed Radiofrequency for Trigeminal Herpes Zoster Neuralgia: A Retrospective Study

Journal of Pain Research
Bo Wang, Ju-Rong Xia, Jin-Yu Li, Zhong-Ju Du, Jian-Ming Yu Department of Anesthesiology and Pain Medicine, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Jian-Ming Yu, Department of ...
Wang B, Xia JR, Li JY, Du ZJ, Yu JM
doaj