Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar +5 more
wiley +1 more source
Differential Cranial Nerve Susceptibility to Compression by a Giant Cerebellopontine Angle Epidermoid Cyst: A Case Report and Literature Review. [PDF]
Díaz Lagunas JO +7 more
europepmc +1 more source
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Basilar Artery Dolichoectasia With Multiple Vessel Compression ("Vessel Sandwich") in Trigeminal Neuralgia: A Case Report and Literature Review. [PDF]
Corpus-Gutiérrez V +9 more
europepmc +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Antinociceptive Effects of Exogenous and Endogenous Carbon Monoxide in the Nitroglycerin-Induced Migraine Model in Rats. [PDF]
Ananev A +5 more
europepmc +1 more source
High‐altitude headache: Insights into pathophysiology and potential treatment implications
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla +3 more
wiley +1 more source
Qualitative validation of TnED©, an electronic instrument capturing pain dimensions in patients with trigeminal neuralgia. [PDF]
Tahiri AS +6 more
europepmc +1 more source
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise +2 more
wiley +1 more source
Editorial: From molecules to function: the world of mesencephalic trigeminal nucleus neurons in health and disease. [PDF]
Bae YC, Toyoda H, Kang Y.
europepmc +1 more source

