Single-nucleus transcriptome analysis reveals transcriptional profiles of circadian clock and pain related genes in human and mouse trigeminal ganglion [PDF]
IntroductionClinical studies have revealed the existence of circadian rhythms in pain intensity and treatment response for chronic pain, including orofacial pain.
Yanhao Chu +23 more
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Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of familial dysautonomia
Familial dysautonomia (FD) is a sensory and autonomic neuropathy caused by mutations in elongator complex protein 1 (ELP1). FD patients have small trigeminal nerves and impaired facial pain and temperature perception.
Carrie E Leonard +3 more
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Trigeminal ganglion innervates the auditory brainstem [PDF]
A neural connection between the trigeminal ganglion and the auditory brainstem was investigated by using retrograde and anterograde tract tracing methods: iontophoretic injections of biocytin or biotinylated dextran-amine (BDA) were made into the guinea pig trigeminal ganglion, and anterograde labeling was examined in the cochlear nucleus and superior ...
Shore, Susan E. +3 more
openaire +4 more sources
Radiofrequency thermocoagulation of Gasserian ganglion in trigeminal neuralgia [PDF]
Introduction: Trigeminal neuralgia (TN) is a form of neuropathic pain that targets the fifth cranial nerve, leading to intense facial pain that can significantly impact one’s quality of life.
Natalia Maria Rulewska +10 more
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Adenovector GAD65 gene delivery into the rat trigeminal ganglion produces orofacial analgesia [PDF]
Background Our goal is to use gene therapy to alleviate pain by targeting glial cells. In an animal model of facial pain we tested the effect of transfecting the glutamic acid decarboxylase (GAD) gene into satellite glial cells (SGCs) of the trigeminal ...
Lowenstein Pedro +9 more
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Percutaneous Trigeminal Ganglion Balloon Compression Rhizotomy: Experience in 27 Patients [PDF]
Purpose. Percutaneous ganglion balloon compression (PBC) is a minimally invasive procedure for treatment of trigeminal neuralgia. Materials and Methods.
Tadej Strojnik, Tomaž Ŝmigoc
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Current understanding of trigeminal ganglion structure and function in headache [PDF]
Introduction The trigeminal ganglion is unique among the somatosensory ganglia regarding its topography, structure, composition and possibly some functional properties of its cellular components. Being mainly responsible for the sensory innervation of
Russo, Andrew F, Messlinger, Karl
core +1 more source
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu +2 more
doaj +1 more source
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu +2 more
doaj +1 more source
Trigeminal ganglion itself can be a viable target to manage trigeminal neuralgia
Excruciating trigeminal neuralgia (TN) management is very difficult and severely affects the patient’s quality of life. Earlier studies have shown that the trigeminal ganglion (TG) comprises several receptors and signal molecules that are involved in the
Elina KC, Jaisan Islam, Young Seok Park
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