Results 71 to 80 of about 105,083 (249)
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
Allergy, EarlyView.ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source
IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells.
PLoS ONE, 2011 ObjectivePro-inflammatory cytokines like Interleukin-1 beta (IL-1β) have been implicated in the pathophysiology of migraine and inflammatory pain.
Lars Neeb +6 more
doaj +1 more source
Molecular Pain, 2020 Allergic contact dermatitis is a skin inflammatory disease manifested with itch and pain symptom around the inflamed area. Chemokines such as CXCL12 are involved in the pathophysiology of allergic contact dermatitis, but little has been known about the ...
Wenliang Su +4 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
BTX-A inhibited trigeminal neuralgia by blocking the NLRP3 pathway in rats
Brain Research BulletinFew studies have examined the mechanisms underlying the development of trigeminal neuralgia involving the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3). The purpose of this experiment was to
Se-Kyung Park +4 more
doaj +1 more source
The Journal of Headache and Pain, 2020 Background Previous studies have reported that electrical stimulation of the motor cortex is effective in reducing trigeminal neuropathic pain; however, the effects of optical motor cortex stimulation remain unclear.
Jaisan Islam +5 more
doaj +1 more source
Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
Brain and Behavior, 2021 This report describes the successful treatment of two patients with trigeminal neuropathy by using gasserian ganglion stimulation. Case reports: The first case report deals with a 53‐year‐old woman suffering from right‐sided facial pain after a gamma ...
Yannick Logghe +5 more
doaj +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system
The Journal of Headache and Pain, 2018 Background Calcitonin gene-related peptide (CGRP) has long been a focus of migraine research, since it turned out that inhibition of CGRP or CGRP receptors by antagonists or monoclonal IgG antibodies was therapeutic in frequent and chronic migraine. This
Karl Messlinger
doaj +1 more source
Retrograde double labeling in the trigeminal ganglion.
, 2014 Representative images two weeks following retrograde labeling of the nasal epithelium (Fluorogold; blue) and middle cerebral artery (MCA) (DiI; red).
Gerry Stephen Oxford (606732) +5 more
core +1 more source