Results 61 to 70 of about 78,976 (362)
Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?
Advanced Therapeutics, EarlyView.The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley +1 more source
Interdisciplinary Neurosurgery, 2021 We present the case of a 53-year-old woman who presented with left-sided atypical facial pain in the V1-V2 distribution of the trigeminal nerve. Further imaging workup revealed a left-sided cavernous aneurysm compressing the V1 and V2 roots of the ...
Anthony S. Larson, B.S +4 more
doaj +1 more source
, 2016 Neuromodulation is a new promising treatment for headache disorders. It consists of peripheral nerve neurostimulation and central neurostimulation. © 2016, Touch Briefings.
Silberstein, Stephen
core +2 more sources
Advanced Science, EarlyView.Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu +13 more
wiley +1 more source
Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
core +2 more sources
Advanced Science, EarlyView.This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan +7 more
wiley +1 more source
Advanced Science, EarlyView.Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao +11 more
wiley +1 more source
Accommodation to Diagnosis of Trigeminal Neuralgia
Acta Clinica Croatica, 2017 Trigeminal neuralgia is one of the most common causes of facial pain. It implies short lasting episodes of unilateral electric shock-like pain with abrupt onset and termination, in the distribution of one or more divisions of the trigeminal nerve that ...
Vanja Bašić Kes, Lucija Zadro Matovina
doaj +1 more source
Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. [PDF]
, 2018 Development of complex neural circuits like the peripheral somatosensory system requires intricate mechanisms to ensure axons make proper connections. While much is known about ligand-receptor pairs required for dorsal root ganglion (DRG) axon guidance ...
Estep, Jason A +5 more
core +2 more sources
Active Whisker‐Inspired Food Material Surface Property Measurement Using Deep‐Learned Mechanosensor
Advanced Intelligent Systems, EarlyView.Herein, a new application is proposed for an active whisker sensor that mimics the movement of rat whiskers. The whiskers, which are deformed by contact with an object, provide information about surface properties. It is shown that active whisker sensors can be useful in the food industry, and data identification is performed using deep learning ...
Jieun Park +13 more
wiley +1 more source