Results 71 to 80 of about 827,907 (400)

Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. [PDF]

open access: yes, 2018
Development of complex neural circuits like the peripheral somatosensory system requires intricate mechanisms to ensure axons make proper connections. While much is known about ligand-receptor pairs required for dorsal root ganglion (DRG) axon guidance ...
Estep, Jason A   +5 more
core   +2 more sources

Multiscale 3D Whole Joint Cellular and Molecular Mapping Reveals Disease‐Specific Neurovascular Plasticity Underlying the Structure‐Pain Relationship

open access: yesAdvanced Science, EarlyView.
This study presents MUSIC, a novel immunostaining and clearing method coupled with large‐field light sheet microscopy, enabling 3D high‐resolution cellular and molecular mapping of intact musculoskeletal joints across species and joint types. Using joint degenerative and injury models, disease‐specific neurovascular alterations are uncovered, revealing
Peng Chen   +18 more
wiley   +1 more source

Anesthesia Dolorosa of Trigeminal Nerve, a Rare Complication of Acoustic Neuroma Surgery

open access: yesCase Reports in Neurological Medicine, 2014
Anesthesia dolorosa is an uncommon deafferentation pain that can occur after traumatic or surgical injury to the trigeminal nerve. This creates spontaneous pain signals without nociceptive stimuli.
Foad Elahi, Kwo Wei David Ho
doaj   +1 more source

Clinical insights on Tolosa Hunt syndrome: a multidisciplinary approach on neurological-related symptomatology in maxillofacial region [PDF]

open access: yes, 2018
Background Tolosa–Hunt syndrome (THS) related neurological symptoms are described in literature as “unilateral”, “recurrent”, “episodic”, “intense”, “severe”, “lancinating” or “stabbing” pain on the upper face and forehead and may be misdiagnosed ...
Ahmed Siddiqui, Ammar   +8 more
core   +2 more sources

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

open access: yesAdvanced Science, EarlyView.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen   +13 more
wiley   +1 more source

Accommodation to Diagnosis of Trigeminal Neuralgia

open access: yesActa Clinica Croatica, 2017
Trigeminal neuralgia is one of the most common causes of facial pain. It implies short lasting episodes of unilateral electric shock-like pain with abrupt onset and termination, in the distribution of one or more divisions of the trigeminal nerve that ...
Vanja Bašić Kes, Lucija Zadro Matovina
doaj   +1 more source

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

open access: yes, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine   +2 more
core   +2 more sources

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Systematic review on the frequency of occurrence in nerve branches and the side of the face involved in trigeminal neuralgia and its clinical implication

open access: yesFrontiers in Neurology
PurposeThe purpose of this systematic review is to answer the focused question, “What is the commonly affected nerve branch and the side of the face involved in trigeminal neuralgia?”Types of studies reviewedThis systematic review included studies ...
Assefa Agegnehu Teshome   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy