Results 81 to 90 of about 771,736 (350)

Variations in Human Trigeminal and Facial Nerve Branches and Foramina Identified by Dissection and Microcomputed Tomography

Clinical Anatomy, EarlyView.
ABSTRACT The aim of this study was to identify branches of the trigeminal and facial nerves (FNs) relevant to surgical incisions and injections and the scalp block techniques in the frontotemporal region, and to determine their relationships with superficial vascular structures and bony landmarks.
Hannah L. Grimes, Valentina Pizzuti, Maria A. Wright, Kane P. J. Colston, Thomas Santarius, Susan Jones   +5 more
wiley   +1 more source

Proximal Nerve Complexes. A Computational Topology Approach [PDF]

arXiv, 2017
This article introduces a theory of proximal nerve complexes and nerve spokes, restricted to the triangulation of finite regions in the Euclidean plane. A nerve complex is a collection of filled triangles with a common vertex, covering a finite region of the plane. Structures called $k$-spokes, $k\geq 1$, are a natural extension of nerve complexes.
arxiv  

A 2‐Part, Open‐Label, Phase 1 Bioequivalence and Food‐Effect Study of Ubrogepant in Healthy Adult Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1 study of ubrogepant was conducted to establish the bioequivalence (BE) of the 50‐ and 100‐mg to‐be‐marketed (TBM) tablet formulations with the clinical trial (CT) 100‐mg tablet formulation and evaluate the food effect on the bioavailability of the 100‐mg TBM tablet. This 2‐part study enrolled healthy participants aged 18‐45 years.
Ramesh Boinpally, Joel M. Trugman
wiley   +1 more source

Iron role paradox in nerve degeneration and regeneration [PDF]

Bolandghamat, S., & Behnam-Rassouli, M. (2024). Iron role paradox in nerve degeneration and regeneration. Physiological Reports, 12, e15908
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de-differentiation. On the other hand, intracellular iron levels remain elevated during nerve regeneration and gradually decrease.
arxiv   +1 more source

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

Clinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang, Logan Brooks, Denise M. Boudreau, Pascal Chanu, Amita Joshi, Bianca Vora, Rui Zhu   +6 more
wiley   +1 more source

Trigeminal nerve electrophysiological findings in hemifacial atrophy: A systematic literature review and retrospective chart review

Clinical Neurophysiology Practice, 2021
Objective: Hemifacial atrophy (HFA) is a rare disorder characterized by progressive unilateral wasting facial soft tissue, muscle, and/or bone. Trigeminal nerve abnormalities may contribute to or result from disease pathophysiology.
Michael P. Skolka, Lisa A. Marks, Lyell K. Jones, Megha M. Tollefson, Jonathan H. Smith   +4 more
doaj  

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

Global Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu, Jian Shi, Can‐Ming Xie, Xiao‐Lei Yao   +3 more
wiley   +1 more source

Cadaveric Anatomical Study of Orbit‐Preserving Ophthalmic Neurectomy via Endoscopic and Exoscopic Techniques

Head &Neck, EarlyView.
ABSTRACT Background Perineural spread of cutaneous head and neck squamous cell carcinoma is most effectively managed by surgical resection with a clear central margin at the affected nerve. For ophthalmic nerve disease, there is no clear consensus regarding the extent of spread which is resectable via an orbit‐preserving neurectomy, either in regard to
Lachlan Crawford, Mark Midwinter, Benedict Panizza   +2 more
wiley   +1 more source

Trigeminal nerve dysfunction in patients with cranial base tumors

Ukrainian Neurosurgical Journal, 2015
Introduction. Impaired function of the trigeminal nerve is often the first and sometimes the only symptom of cranial base tumors.Materials and methods.
Mykola Polishchuk, Oleksandr Voznyak, Anatoliy Kaminskiy, Andrey Oblyvach, Vakhtang Sichinava, Maksim Gudim   +5 more
doaj   +1 more source

Post-Traumatic Trigeminal Neuropathy: Neurobiology and Pathophysiology

Biology
Painful traumatic trigeminal neuropathy (PTTN) is a chronic neuropathic pain that may develop following injury to the trigeminal nerve. Etiologies include cranio-orofacial trauma that may result from dental, surgical, or anesthetic procedures or physical
Tal Eliav, Rafael Benoliel, Olga A. Korczeniewska   +2 more
doaj   +1 more source