Results 171 to 180 of about 1,572,766 (300)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Plantar pressures and stabilometry effects of ischemic compression in Flexor digitorum brevis muscle Myofascial Trigger Point: A prepost study. [PDF]

PLoS One
Martínez-Jiménez EM, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Pérez-Boal E, Posada-Ordax J, Sánchez-Serena A, Trevissón-Redondo B, Benito-de-Pedro M, Martínez-Córcoles V, Casado-Hernández I.   +9 more
europepmc   +1 more source

Utilizing an ultrasound guided 5-in-1 trigger point and hydrodissection technique for interscapular mid-thoracic myofascial pain: A retrospective review. [PDF]

Interv Pain Med, 2023
Modi DJ, Tuttle JM, Kang S, Singh JR.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Effectiveness of pelvic myofascial trigger point release for the therapy of sexual dysfunction in women after vaginal delivery: A prospective pilot study. [PDF]

Turk J Phys Med Rehabil
Mao YR, Fan W, Zhu Y, Gu Q, Jin Q, Liu Z.   +5 more
europepmc   +1 more source

Effectiveness of Manual Trigger Point Therapy in Patients with Myofascial Trigger Points in the Orofacial Region-A Systematic Review. [PDF]

Life (Basel), 2023
Müggenborg F, de Castro Carletti EM, Dennett L, de Oliveira-Souza AIS, Mohamad N, Licht G, von Piekartz H, Armijo-Olivo S.   +7 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Ultrasound-Guided Stellate Ganglion Block with Cervicotemporal Myofascial Trigger Point Acupuncture for Insomnia with Comorbid Anxiety and Depression: A Retrospective Observational Study. [PDF]

Nat Sci Sleep
Li Z, Wang L, Cong P, Chen S, Wang J, Zhang H, Zhao J, Li G, Jiao F, Li L, Wang R, Wu Q, Gong M, Chen Z, Wang Y.   +14 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Painful Flexible Flatfoot Deformity: A Description of Posterolateral Ankle Trigger Point for Pain. [PDF]

Cureus
Kassab F, Sonbol AM.
europepmc   +1 more source