Results 71 to 80 of about 390,866 (257)
Effectiveness of peripheral neurectomy in refractory cases of trigeminal neuralgia
Context: Trigeminal neuralgia (TN) is a commonly diagnosed neurosensory disease of orofacial region involving the fifth cranial nerve. Patient refractory to pharmacotherapy or with clinical and/or laboratory side effects sufficient to demand drug ...
Narayan Sharma Lamichhane +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Ma YT, Li LH, Han Q, et al. J Pain Res. 2020;13:1677–1686. The authors have advised Figure 3 on page 1682 is incorrect. Due to an error at the time of figure assembly Figure 2 and Figure 3 were duplicated.
Ma YT +6 more
doaj
Background It is still unclear when latent myofascial trigger points (MTrPs) develop during early life. This study is designed to investigate the mechanical pain sensitivity of deep tissues in children in order to see the possible timing of the ...
Han Ting-I +5 more
doaj +1 more source
Myofascial Trigger Points [PDF]
To the Editor: I am a practicing physical therapist in a private orthopedic and sports medicine practice in downtown Manhattan. In my practice, a vast majority of my patients have cervical, scapular, and thoracic pain as well as headaches with related trigger points throughout the scapular musculature.
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Background: Plantar fasciitis is the most common cause of heel pain. Extracorporeal shock wave therapy (ESWT) is an alternative treatment for refractory cases of plantar fasciitis.
Alireza Moghtaderi +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

