Results 91 to 100 of about 1,148,661 (279)

Magnitude Clustering During Stick‐Slip Dynamics on Laboratory Faults

open access: yesGeophysical Research Letters
We present an analysis of magnitude clustering of microfractures inferred from acoustic emissions (AEs) during stick‐slip (SS) dynamics of faulted Westerly granite samples in frictional sliding experiments, with and without fluids, under triaxial loading
Omid Khajehdehi   +3 more
doaj   +1 more source

Medicanes Triggering Chlorophyll Increase

open access: yesJournal of Marine Science and Engineering, 2019
Studies have shown that hurricanes and typhoons, apart from being extreme weather phenomena, cause increases in marine chlorophyll-a concentrations and even phytoplankton blooms.
Dionysia Kotta, Dimitra Kitsiou
doaj   +1 more source

Triggering an aurora [PDF]

open access: yes
Ambient ionospheric electron density studied as triggering mechanism of ...
Linson, L. M., Petschek, H. E.
core   +1 more source

The 2007 Azores earthquakes: A case of triggering? [PDF]

open access: yes, 2009
On 5 April (Mw=6.3) and 7 April 2007 (Mw=6.1 ) two earthquakes occur at the Formigas Islets (Azores Islands), both with same epicenter and felt (I=V/VI MSK) in S. Miguel Island.
Bezzghoud, M   +3 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Time-triggering versus event-triggering control over communication channels

open access: yes, 2017
Time-triggered and event-triggered control strategies for stabilization of an unstable plant over a rate-limited communication channel subject to unknown, bounded delay are studied and compared.
Cortes, Jorge   +3 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Comparison of different inspiratory triggering settings in automated ventilators during cardiopulmonary resuscitation in a porcine model.

open access: yesPLoS ONE, 2017
BackgroundMechanical ventilation via automated in-hospital ventilators is quite common during cardiopulmonary resuscitation. It is not known whether different inspiratory triggering sensitivity settings of ordinary ventilators have different effects on ...
Dingyu Tan   +9 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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