Results 51 to 60 of about 1,148,661 (279)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]

, 2018
We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F., Ceol M, Cristofaro R, Del Prete D, Furlan C, Gianesello L, Priante G, Quaggio F, Terrin L   +8 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Decay acceleration of isomers by X-ray laser [PDF]

Ядерна фізика та енергетика, 2010
We analyzed the possibility of the two-step triggering of nuclear isomers by short X-ray laser pulses via an excited intermediate level. The estimations of the decay acceleration are performed for the 6− isomer of 84Rb in the field of future European X ...
A. Ya. Dzyublik
doaj  

Landslide Susceptibility Assessment at the Basin Scale for Rainfall- and Earthquake-Triggered Shallow Slides

Geosciences, 2019
The hydrographic basin of Ribeira Grande (S. Miguel Island, Azores) has a set of characteristics that enhance the occurrence of shallow slides that have been triggered by rainfall and earthquakes.
Cristina Gordo, José Luís Zêzere, Rui Marques   +2 more
doaj   +1 more source

Apparent Clustering and Apparent Background Earthquakes Biased by Undetected Seismicity

, 2005
In models of triggered seismicity and in their inversion with empirical data, the detection threshold m_d is commonly equated to the magnitude m_0 of the smallest triggering earthquake. This unjustified assumption neglects the possibility of shocks below
Ben-Zion, Console, Didier Sornette, Dieterich, Felzer, Helmstetter, Helmstetter, Helmstetter, Helmstetter, Helmstetter, Helmstetter, Helmstetter, Kagan, Kagan, Kagan, Kagan, Maximillian J. Werner, Nechad, Ogata, Ogata, Ouillon, Reasenberg, Richardson, Sellers, Sornette, Sornette, Sornette, Utsu, Zhuang   +28 more
core   +1 more source

Triggering magnetar outbursts in 3D force-free simulations [PDF]

, 2019
In this letter, we present the first 3D force-free general relativity simulations of the magnetosphere dynamics related to the magnetar outburst/flare phenomenology. Starting from an initial dipole configuration, we adiabatically increase the helicity by
Carrasco, Federico, Palenzuela, Carlos, Pons, Jose A., Viganò, Daniele   +3 more
core   +3 more sources

Transport-triggering vs. operation-triggering [PDF]

, 1994
Transport-triggered architectures are a new class of architectures that provide more scheduling freedom and have unique compiler optimizations. This paper reports experiments that quantify the advantages of transport-triggered architectures with respect to traditional operation-triggered architectures.
Jan Hoogerbrugge, Henk Corporaal
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Triggering of Land Subsidence in and Surrounding the Hangjiahu Plain Based on Interferometric Synthetic Aperture Radar Monitoring

Remote Sensing
In the early stages, uncontrolled groundwater extraction led to the Hangjiahu (HJH) Plain becoming one of the areas with the most severe land subsidence in China.
Zixin He, Zimeng Yang, Xiaoyong Wu, Tingting Zhang, Mengning Song, Ming Liu   +5 more
doaj   +1 more source