Results 121 to 130 of about 487,773 (305)

Pomegranate Juice Protects Macrophages from Triglyceride Accumulation: Inhibitory Effect on DGAT1 Activity and on Triglyceride Biosynthesis

open access: yes, 2011
<i>Background/Aims:</i> To analyze the effects of pomegranate juice (PJ) and punicalagin on macrophage triglyceride metabolism. <i>Methods:</i> Triglyceride metabolism was analyzed in PJ- or punicalagin-treated J774A.1 macrophages
Mira Rosenblat, Michael Aviram
core   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

Triglyceride-glucose index association with severity of coronary artery disease

open access: yes
BackgroundDespite previous studies, the relationship between the triglyceride-glucose (TyG) index and coronary artery disease (CAD) is still undetermined.
M Marousi (21646766)   +8 more
core  

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

open access: yesAdvanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu   +4 more
wiley   +1 more source

Diagnostic Odyssey of Atypical Long‐Chain 3‐Hydroxyacyl‐CoA Dehydrogenase Deficiency (LCHADD) Explained by Three Allelic Products From Two Pathogenic Variants

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta   +9 more
wiley   +1 more source

Triglyceride storage in skeletal muscle

open access: yes, 2008
When muscle fibres contract they rely on fuels from extra-and intramuscular fat and carbohydrate sources. The most important fuels are free fatty acids from blood and intramuscular triglyceride stores and glucose from blood and intramuscular glycogen ...
Essén-Gustavsson, Birgitta
core  

Identified mutants in triglyceride metabolism.

open access: yes, 2013
Identified mutants in triglyceride metabolism.
Andreas Mayer (187816)   +1 more
core   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy   +16 more
wiley   +1 more source

Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics

open access: yesAngewandte Chemie, EarlyView.
This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang   +9 more
wiley   +2 more sources

Glycerol, Triglyceride and Oxidative stress

open access: yes, 2017
Measurements of Glycerol, Triglyceride and Oxidative ...
Yap, Kang Nian   +7 more
core   +1 more source

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