Results 11 to 20 of about 593,958 (297)

Knockdown of lnc-KCNC3-3:1 Alleviates the Development of Atherosclerosis via Downregulation of JAK1/STAT3 Signaling Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is a major cause of coronary artery disease (CAD), and CAD is one of the main causes leading to death in most countries. It has been reported that lncRNAs play important roles in the development of atherosclerosis; thus, we ...
Limin Sun   +4 more
doaj   +1 more source

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

open access: yes, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A.   +9 more
core   +2 more sources

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis

open access: yesBiomedicines, 2021
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee   +5 more
doaj   +1 more source

Studies on hepatotoxicity induced by chlorinated hydrocarbons. Lipid and ATP metabolisms in the liver of mice exposed to 1,1,2,2-tetrachloroethane [PDF]

open access: yes, 1969
With a constant gas-exposure chamber newly devised, the author had Cb mice (females weighing 16.0 ± 1.5 g) inhale 600 ppm (in average) of 1, 1, 2, 2-tetrachloroethane for 3 hours.
Tomokuni, Katsumaro
core   +1 more source

Triglyceride [PDF]

open access: yesCirculation, 1998
The relation of serum TG concentrations and risk for CHD has been an issue of great interest and controversy. Unlike analyses with LDL-C and HDL-C, for which very strong and consistent relations with CHD risk have been demonstrated in observational and interventional studies, those with TG are ambiguous. Thus, TG represents a clinical conundrum: should
openaire   +1 more source

The Long Term Kinetic of Plasma Lipids and Lipoproteins in Tyloxapol Injected Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The level of plasma triglyceride is balanced by the rate of secretion into and clearance from the plasma. Tyloxapol (Triton WR1339) is a nonionic detergent that inhibits lipoprotein lipase and hence clearance of triglyceride from the ...
Mehdi Rasouli   +2 more
doaj   +1 more source

Colorimetric Measurement of Triglycerides Cannot Provide an Accurate Measure of Stored Fat Content in Drosophila [PDF]

open access: yes, 2010
Drosophila melanogaster has recently emerged as a useful model system in which to study the genetic basis of regulation of fat storage. One of the most frequently used methods for evaluating the levels of stored fat (triglycerides) in flies is a coupled ...
Andreas Bergmann   +19 more
core   +8 more sources

Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene

open access: yesJournal of Lipid Research, 2002
Missense mutations in exon 5 of the LPL gene are the most common reported cause of LPL deficiency. Exon 5 is also the region with the strongest homology to pancreatic and hepatic lipase, and is conserved in LPL from different species. Mutant LPL proteins
Jonas Peterson   +8 more
doaj   +1 more source

Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans

open access: yesJournal of Lipid Research, 2004
Hepatic lipase activity (HLA) is a determinant of HDL levels, and a polymorphism in the hepatic lipase gene (LIPC) promoter (C−514T) has been hypothesized to account for higher HDL in blacks and Japanese compared with whites.
Molly C. Carr   +2 more
doaj   +1 more source

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