Results 231 to 240 of about 869,613 (345)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Association of Triglyceride With Incident Cancer: An Analysis of the Whole-Body Cancer Screening Program in Japan. [PDF]

Health Sci Rep
Teramukai S, Torizuka T, Sakabayashi S, Shinke T, Okada H, Kikuchi T, Nishizawa S, Fukushima M.   +7 more
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Positive association between different triglyceride-glucose index-related indicators and overactive bladder: Results from NHANES (2013-2020). [PDF]

Medicine (Baltimore)
Luo Y, Li S, Lu Y, Hou D, Yang J.
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Correction: Association between TyG-BMI and early-onset hypertension: evidence from NHANES. [PDF]

Sci Rep
Li W, Ge C, Zhou J.
europepmc   +1 more source

Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state.

Arteriosclerosis and Thrombosis A Journal of Vascular Biology, 1992
J. R. Patsch, G. Miesenbock, T. Hopferwieser, V. Muhlberger, E. Knapp, J. Dunn, A. Gotto, W. Patsch   +7 more
semanticscholar   +1 more source

Synergistic Effects of Normal‐Range Serum Sodium and Potassium on Mortality: The Modifying Role of Inflammation From a NHANES Cohort Analysis

Chronic Diseases and Translational Medicine, EarlyView.
Nonlinear associations of serum sodium levels with cardiovascular (A) and all‐cause mortality (B)among 32,837 adults. Nonlinear associations of serum potassium levels with cardiovascular (C) and all‐cause mortality (D) among 32,837 adults. ABSTRACT Background This study aimed to investigate the associations of serum sodium and potassium levels within ...
Haofeng Zhang, Fudong He, Zhenger Fang, Guangjun Zheng, Biying Zhou, Xia Chen, Mingliang Liu, Guang Hao   +7 more
wiley   +1 more source

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology, 2007
K. Yamaguchi, Liu Yang, S. McCall, Jiawen Huang, Xing Yu, S. Pandey, S. Bhanot, B. Monia, Yin-xiong Li, A. Diehl   +9 more
semanticscholar   +1 more source